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Fhip2b FHF complex subunit HOOK interacting protein 2B [ Mus musculus (house mouse) ]

Gene ID: 239170, updated on 5-Mar-2024

Summary

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Official Symbol
Fhip2bprovided by MGI
Official Full Name
FHF complex subunit HOOK interacting protein 2Bprovided by MGI
Primary source
MGI:MGI:3036290
See related
Ensembl:ENSMUSG00000022095 AllianceGenome:MGI:3036290
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rai16; Fam160b2; G430067P06Rik
Summary
Orthologous to human FHIP2B (FHF complex subunit HOOK interacting protein 2B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 22.3), ovary adult (RPKM 22.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Fhip2b in Genome Data Viewer
Location:
14 D2; 14 36.32 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (70820733..70837309, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (70583295..70599835, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8570 Neighboring gene predicted gene, 53866 Neighboring gene nudix hydrolase 18 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:70999253-70999362 Neighboring gene dematin actin binding protein Neighboring gene STARR-seq mESC enhancer starr_37085 Neighboring gene predicted gene, 38605 Neighboring gene fibroblast growth factor 17

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Retinoic acid induced 16 deficiency exacerbates high-fat diet-induced steatohepatitis in mice. Qian CL, et al. Cell Biochem Funct, 2020 Aug. PMID 32289885
  2. Retinoid acid induced 16 deficiency aggravates colitis and colitis-associated tumorigenesis in mice. Xu YL, et al. Cell Death Dis, 2019 Dec 20. PMID 31862898, Free PMC Article
  3. Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species. Tonelli Gombalová Z, et al. J Comp Neurol, 2020 Oct 15. PMID 32212159
  4. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  5. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Retinoic acid induced 16 deficiency exacerbates high-fat diet-induced steatohepatitis in mice.
    Title: Retinoic acid induced 16 deficiency exacerbates high-fat diet-induced steatohepatitis in mice.
  2. Retinoid acid induced 16 deficiency aggravates colitis and colitis-associated tumorigenesis in mice.
    Title: Retinoid acid induced 16 deficiency aggravates colitis and colitis-associated tumorigenesis in mice.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
FHF complex subunit HOOK-interacting protein 2B
Names
family with sequence similarity 160, member B2
protein FAM160B2
retinoic acid induced 16
retinoic acid-induced protein 16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_194345.1 → NP_919326.1  FHF complex subunit HOOK-interacting protein 2B

    See identical proteins and their annotated locations for NP_919326.1

    Status: VALIDATED

    Source sequence(s)
    AC154563, BC058108, BM942664, BU152183, CD348387, CF170130, CN529793
    Consensus CDS
    CCDS49537.1
    UniProtKB/Swiss-Prot
    Q6PED9, Q80YR2, Q8C1Y2
    Related
    ENSMUSP00000022690.10, ENSMUST00000022690.10
    Conserved Domains (1) summary
    pfam10257
    Location:79 → 477
    RAI16-like; Retinoic acid induced 16-like protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    70820733..70837309 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036158590.1 → XP_036014483.1  FHF complex subunit HOOK-interacting protein 2B isoform X1

    Conserved Domains (1) summary
    pfam10257
    Location:79 → 442
    RAI16-like; Retinoic acid induced 16-like protein

  2. XM_006518998.4 → XP_006519061.1  FHF complex subunit HOOK-interacting protein 2B isoform X2

    Conserved Domains (1) summary
    pfam10257
    Location:10 → 387
    RAI16-like; Retinoic acid induced 16-like protein

  3. XM_017316016.3 → XP_017171505.1  FHF complex subunit HOOK-interacting protein 2B isoform X3

    Conserved Domains (1) summary
    pfam10257
    Location:3 → 186
    RAI16-like; Retinoic acid induced 16-like protein

  4. XM_036158591.1 → XP_036014484.1  FHF complex subunit HOOK-interacting protein 2B isoform X3

    Conserved Domains (1) summary
    pfam10257
    Location:3 → 186
    RAI16-like; Retinoic acid induced 16-like protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80YR2.2 GenPept UniProtKB/Swiss-Prot:Q80YR2

Gene LinkOut

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