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Krt39 keratin 39 [ Mus musculus (house mouse) ]

Gene ID: 237934, updated on 5-Mar-2024

Summary

Official Symbol
Krt39provided by MGI
Official Full Name
keratin 39provided by MGI
Primary source
MGI:MGI:3588208
See related
Ensembl:ENSMUSG00000064165 AllianceGenome:MGI:3588208
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ka35; 4732494G06Rik
Summary
Predicted to enable structural molecule activity. Predicted to be located in intermediate filament. Orthologous to human KRT39 (keratin 39). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

Location:
11 D; 11 62.92 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (99403786..99412164, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (99512960..99521338, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene keratin 20 Neighboring gene keratin 23 Neighboring gene STARR-seq mESC enhancer starr_30705 Neighboring gene keratin 40 Neighboring gene keratin associated protein 3-3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in epithelial cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermediate filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
keratin, type I cytoskeletal 39
Names
CK-39
K39
cytokeratin-39
ortholog of type I hair keratin KA35
type I hair keratin KA35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213730.3NP_998895.2  keratin, type I cytoskeletal 39

    See identical proteins and their annotated locations for NP_998895.2

    Status: VALIDATED

    Source sequence(s)
    AL591417
    Consensus CDS
    CCDS25383.1
    UniProtKB/Swiss-Prot
    A2VCT4, Q0VDS4, Q6IFX4
    Related
    ENSMUSP00000076216.2, ENSMUST00000076948.2
    Conserved Domains (1) summary
    pfam00038
    Location:91401
    Filament; Intermediate filament protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    99403786..99412164 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)