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Slfn10-ps schlafen 10, pseudogene [ Mus musculus (house mouse) ]

Gene ID: 237887, updated on 8-Feb-2024

Summary

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Official Symbol
Slfn10-psprovided by MGI
Official Full Name
schlafen 10, pseudogeneprovided by MGI
Primary source
MGI:MGI:3512288
See related
Ensembl:ENSMUSG00000121398 AllianceGenome:MGI:3512288
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Slfn10; mFLJ00257
Summary
Orthologous to human SLFN13 (schlafen family member 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
11 C; 11 50.3 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (82918949..82931359, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (83028123..83040533, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene schlafen 8 Neighboring gene STARR-seq mESC enhancer starr_30184 Neighboring gene 60S ribosomal protein L12 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E10699 Neighboring gene STARR-positive B cell enhancer ABC_E8434 Neighboring gene STARR-positive B cell enhancer ABC_E7028 Neighboring gene STARR-positive B cell enhancer ABC_E5255 Neighboring gene STARR-positive B cell enhancer mm9_chr11:82877709-82878010 Neighboring gene predicted gene, 20234 Neighboring gene STARR-seq mESC enhancer starr_30185 Neighboring gene schlafen 2 Neighboring gene STARR-seq mESC enhancer starr_30186 Neighboring gene predicted gene, 53233 Neighboring gene schlafen 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Modulation of T cell development and activation by novel members of the Schlafen (slfn) gene family harbouring an RNA helicase-like motif. Geserick P, et al. Int Immunol, 2004 Oct. PMID 15351786
  2. Evolution of the Schlafen genes, a gene family associated with embryonic lethality, meiotic drive, immune processes and orthopoxvirus virulence. Bustos O, et al. Gene, 2009 Nov 1. PMID 19619625, Free PMC Article
  3. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Clone Names

  • FLJ00257

General protein information

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Preferred Names
schlafen 10
Names
Schlafen family member 10 homologue

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355513.1 → NP_001342442.1  schlafen 10

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents the protein-coding allele present in the CAST/EiJ strain genome.
    Source sequence(s)
    LT629148
    UniProtKB/TrEMBL
    A0A1G5SJ64, A0A1G5SJ80
    Conserved Domains (3) summary
    cl22977
    Location:870 → 913
    UvrD_C_2; UvrD-like helicase C-terminal domain
    cl26594
    Location:613 → 779
    DUF2075; Uncharacterized conserved protein (DUF2075)
    cl27772
    Location:64 → 363
    B3R; Poxviridae B3 protein

RNA

  1. NR_073523.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AK220241, BP765349
    Related
    ENSMUST00000100716.11

  2. NR_073524.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2, noncoding) represents the non-functional allele found in the reference genome and uses an alternate 5' terminal exon compared to variant 1.
    Source sequence(s)
    AK041394, AY261802, BP765349

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    82918949..82931359 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_181542.4: Suppressed sequence

    Description
    NM_181542.4: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
Nucleotide Protein Strain
Heading Accession and Version

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