Nsrp1 nuclear speckle regulatory protein 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Nsrp1provided by MGI
Official Full Name: nuclear speckle regulatory protein 1provided by MGI
Primary source: MGI:MGI:2144305
See related: Ensembl:ENSMUSG00000037958 AllianceGenome:MGI:2144305
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Ccdc55; NSpr70; NSrp70; 8030451K07
Summary: Predicted to enable mRNA binding activity. Acts upstream of or within in utero embryonic development. Predicted to be located in nuclear speck. Predicted to be part of ribonucleoprotein complex. Orthologous to human NSRP1 (nuclear speckle splicing regulatory protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E11.5 (RPKM 7.3), placenta adult (RPKM 3.5) and 19 other tissues See more
Orthologs: human all
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Genomic context

Location:: 11 B5; 11 46.21 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (76935118..76969263, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (77044292..77078437, complement)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

NSrp70 is a lymphocyte-essential splicing factor that controls thymocyte development.
Title: NSrp70 is a lymphocyte-essential splicing factor that controls thymocyte development.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Gene trapped (1)
Targeted (2) 1 citation
Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D11Mit280 (e-PCR), detects polymorphism
- UniSTS:126487

NoName (e-PCR)
- UniSTS:236648

AI851076 (e-PCR)
- UniSTS:164469

RH125374 (e-PCR)
- UniSTS:162196

px-38e3 (e-PCR)
- UniSTS:257695

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA splicing	IEA Inferred from Electronic Annotation more info
involved_in developmental process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within in utero embryonic development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in regulation of alternative mRNA splicing, via spliceosome	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in nuclear speck	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of ribonucleoprotein complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: nuclear speckle splicing regulatory protein 1

Names: coiled-coil domain containing 55; coiled-coil domain-containing protein 55; nuclear speckle-related protein 70

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.