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Gm4922 predicted gene 4922 [ Mus musculus (house mouse) ]

Gene ID: 237300, updated on 11-Apr-2024

Summary

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Official Symbol
Gm4922provided by MGI
Official Full Name
predicted gene 4922provided by MGI
Primary source
MGI:MGI:3644318
See related
Ensembl:ENSMUSG00000044624 AllianceGenome:MGI:3644318
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EG237300; 4933423E17
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and protein phosphorylation. Predicted to act upstream of or within phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 3.9) See more
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Genomic context

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Location:
10 A3; 10 7.92 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (18655475..18662541, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (18779727..18786793, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_25912 Neighboring gene heme binding protein 2 Neighboring gene ARFGEF family member 3 Neighboring gene STARR-seq mESC enhancer starr_25915 Neighboring gene STARR-seq mESC enhancer starr_25916 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:18384699-18384900 Neighboring gene predicted gene, 32926 Neighboring gene STARR-seq mESC enhancer starr_25918 Neighboring gene RIKEN cDNA 4930444F02 gene Neighboring gene PERP, TP53 apoptosis effector

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The mouse kinome: discovery and comparative genomics of all mouse protein kinases. Caenepeel S, et al. Proc Natl Acad Sci U S A, 2004 Aug 10. PMID 15289607, Free PMC Article
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. First described as a mouse-specific duplication of the MARK kinase family, and named as MarkmA1.
    Title: The mouse kinome: discovery and comparative genomics of all mouse protein kinases.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
sperm motility kinase Z
NP_808374.1
XP_017169423.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177706.4 → NP_808374.1  sperm motility kinase Z

    See identical proteins and their annotated locations for NP_808374.1

    Status: PROVISIONAL

    Source sequence(s)
    AK030207
    Consensus CDS
    CCDS48509.1
    UniProtKB/Swiss-Prot
    Q8C0N0
    Related
    ENSMUSP00000149756.2, ENSMUST00000216654.2
    Conserved Domains (2) summary
    cd14337
    Location:293 → 330
    UBA_MARK_Par1; UBA domain found in microtubule-associated protein (MAP)/microtubule affinity-regulating kinase (MARK)/ partitioning-defective 1 (Par-1) and similar proteins
    cd14003
    Location:27 → 274
    STKc_AMPK-like; Catalytic domain of AMP-activated protein kinase-like Serine/Threonine Kinases

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    18655475..18662541 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017313934.1 → XP_017169423.1  sperm motility kinase Z isoform X1

    UniProtKB/Swiss-Prot
    Q8C0N0
    Related
    ENSMUSP00000055273.7, ENSMUST00000055107.7
    Conserved Domains (2) summary
    cd14337
    Location:293 → 330
    UBA_MARK_Par1; UBA domain found in microtubule-associated protein (MAP)/microtubule affinity-regulating kinase (MARK)/ partitioning-defective 1 (Par-1) and similar proteins
    cd14003
    Location:27 → 274
    STKc_AMPK-like; Catalytic domain of AMP-activated protein kinase-like Serine/Threonine Kinases
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C0N0.1 GenPept UniProtKB/Swiss-Prot:Q8C0N0

Gene LinkOut

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