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Zfp825 zinc finger protein 825 [ Mus musculus (house mouse) ]

Gene ID: 235956, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp825provided by MGI
Official Full Name
zinc finger protein 825provided by MGI
Primary source
MGI:MGI:2385315
See related
Ensembl:ENSMUSG00000069208 AllianceGenome:MGI:2385315
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in genitourinary system. Orthologous to human ZNF101 (zinc finger protein 101). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 1.2), CNS E11.5 (RPKM 1.1) and 24 other tissues See more
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Genomic context

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Location:
13 C1; 13 40.33 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (74626497..74642132, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (74478378..74494012, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_35009 Neighboring gene predicted gene, 41004 Neighboring gene RIKEN cDNA E430024I08 gene Neighboring gene STARR-seq mESC enhancer starr_35011 Neighboring gene predicted gene, 57595 Neighboring gene STARR-positive B cell enhancer ABC_E4079 Neighboring gene STARR-positive B cell enhancer ABC_E9401 Neighboring gene STARR-seq mESC enhancer starr_35015 Neighboring gene upstream binding transcription factor, RNA polymerase I pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E7252 Neighboring gene stomatin (Epb7.2)-like 2 pseudogene Neighboring gene predicted gene, 57808 Neighboring gene predicted gene, 57809

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex. Ulmke PA, et al. Stem Cell Reports, 2021 Apr 13. PMID 33798452, Free PMC Article
  2. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC18736

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 124

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001374752.1 → NP_001361681.1  zinc finger protein 124 isoform 1

    Status: VALIDATED

    Source sequence(s)
    CT009718
    Consensus CDS
    CCDS88485.1
    UniProtKB/TrEMBL
    A0A1Y7VK00
    Conserved Domains (3) summary
    COG5048
    Location:119 → 271
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:207 → 227
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:22 → 62
    KRAB; KRAB box

  2. NM_001377115.1 → NP_001364044.1  zinc finger protein 124 isoform 1

    Status: VALIDATED

    Source sequence(s)
    CT009718
    UniProtKB/TrEMBL
    A0A1Y7VK00
    Related
    ENSMUSP00000152719.2, ENSMUST00000221173.2
    Conserved Domains (3) summary
    COG5048
    Location:119 → 271
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:207 → 227
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:22 → 62
    KRAB; KRAB box

  3. NM_146231.2 → NP_666343.1  zinc finger protein 124 isoform 2

    See identical proteins and their annotated locations for NP_666343.1

    Status: VALIDATED

    Source sequence(s)
    CT009718
    Consensus CDS
    CCDS79212.1
    UniProtKB/TrEMBL
    Q91VL6
    Related
    ENSMUSP00000144128.2, ENSMUST00000202645.4
    Conserved Domains (3) summary
    COG5048
    Location:101 → 253
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:189 → 209
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4 → 44
    KRAB; KRAB box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    74626497..74642132 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030247254.2 → XP_030103114.1  zinc finger protein 124 isoform X1

    Related
    ENSMUSP00000073973.7, ENSMUST00000074369.7
    Conserved Domains (2) summary
    COG5048
    Location:69 → 221
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:157 → 177
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_036158036.1 → XP_036013929.1  zinc finger protein 124 isoform X1

    Conserved Domains (2) summary
    COG5048
    Location:69 → 221
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:157 → 177
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein
Heading Accession and Version

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