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Atosa atos homolog A [ Mus musculus (house mouse) ]

Gene ID: 235493, updated on 21-Apr-2024

Summary

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Official Symbol
Atosaprovided by MGI
Official Full Name
atos homolog Aprovided by MGI
Primary source
MGI:MGI:2387648
See related
Ensembl:ENSMUSG00000034858 AllianceGenome:MGI:2387648
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam214a; Kiaa1370; mKIAA1370; 6330415I01Rik; C130047D21Rik
Summary
Is expressed in endocrine gland; hindlimb mesenchyme; jaw; rib; and testis. Orthologous to human FAM214A (family with sequence similarity 214 member A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in subcutaneous fat pad adult (RPKM 5.9), frontal lobe adult (RPKM 5.6) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
9 D; 9 42.12 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (74860162..74939750)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (74952867..75032468)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33562 Neighboring gene STARR-seq mESC enhancer starr_24650 Neighboring gene predicted gene 16551 Neighboring gene one cut domain, family member 1 Neighboring gene predicted gene, 38678 Neighboring gene STARR-positive B cell enhancer ABC_E8300 Neighboring gene STARR-positive B cell enhancer ABC_E6765 Neighboring gene STARR-positive B cell enhancer ABC_E714 Neighboring gene STARR-positive B cell enhancer mm9_chr9:74812784-74813085 Neighboring gene STARR-positive B cell enhancer mm9_chr9:74813338-74813639 Neighboring gene microRNA 1970c Neighboring gene STARR-seq mESC enhancer starr_24651 Neighboring gene STARR-seq mESC enhancer starr_24653 Neighboring gene STARR-positive B cell enhancer ABC_E10563 Neighboring gene predicted gene, 51714 Neighboring gene cAMP-regulated phosphoprotein 19 Neighboring gene apoptosis inhibitor 5 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models. Soulez M, et al. Mol Cell Biol, 2019 Mar 15. PMID 30642949, Free PMC Article
  2. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC38960, MGC41344

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
atos homolog protein A
Names
family with sequence similarity 214, member A
protein FAM214A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113283.1 → NP_001106754.1  atos homolog protein A isoform 1

    See identical proteins and their annotated locations for NP_001106754.1

    Status: VALIDATED

    Source sequence(s)
    CT025657, CT033761
    Consensus CDS
    CCDS52857.1
    UniProtKB/Swiss-Prot
    E9PX00, Q69ZK7, Q8K0I6, Q8K266
    UniProtKB/TrEMBL
    A0A1L1SSW7
    Related
    ENSMUSP00000129319.2, ENSMUST00000170846.8
    Conserved Domains (2) summary
    pfam13915
    Location:878 → 935
    DUF4210; Domain of unknown function (DUF4210)
    pfam13889
    Location:1017 → 1074
    Chromosome_seg; Chromosome segregation during meiosis

  2. NM_001359816.1 → NP_001346745.1  atos homolog protein A isoform 1

    Status: VALIDATED

    Source sequence(s)
    CT025657, CT033761
    Consensus CDS
    CCDS52857.1
    UniProtKB/Swiss-Prot
    E9PX00, Q69ZK7, Q8K0I6, Q8K266
    UniProtKB/TrEMBL
    A0A1L1SSW7
    Conserved Domains (2) summary
    pfam13915
    Location:878 → 935
    DUF4210; Domain of unknown function (DUF4210)
    pfam13889
    Location:1017 → 1074
    Chromosome_seg; Chromosome segregation during meiosis

  3. NM_153584.2 → NP_705812.2  atos homolog protein A isoform 2

    Status: VALIDATED

    Source sequence(s)
    AW990238, BC031353, BU057452
    Consensus CDS
    CCDS52858.1
    UniProtKB/TrEMBL
    A0A1L1SSW7
    Related
    ENSMUSP00000080442.6, ENSMUST00000081746.7
    Conserved Domains (2) summary
    pfam13889
    Location:1024 → 1081
    Chromosome_seg; Chromosome segregation during meiosis
    pfam13915
    Location:885 → 942
    DUF4210; Domain of unknown function (DUF4210)

RNA

  1. NR_153342.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    CT025657, CT033761

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    74860162..74939750
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511126.5 → XP_006511189.1  atos homolog protein A isoform X1

    See identical proteins and their annotated locations for XP_006511189.1

    UniProtKB/Swiss-Prot
    E9PX00, Q69ZK7, Q8K0I6, Q8K266
    UniProtKB/TrEMBL
    A0A1L1SSW7
    Related
    ENSMUSP00000149021.2, ENSMUST00000215370.2
    Conserved Domains (2) summary
    pfam13915
    Location:878 → 935
    DUF4210; Domain of unknown function (DUF4210)
    pfam13889
    Location:1017 → 1074
    Chromosome_seg; Chromosome segregation during meiosis

  2. XM_036154910.1 → XP_036010803.1  atos homolog protein A isoform X2

    UniProtKB/TrEMBL
    A0A1L1SSW7
    Conserved Domains (2) summary
    pfam13889
    Location:929 → 986
    Chromosome_seg; Chromosome segregation during meiosis
    pfam13915
    Location:790 → 847
    DUF4210; Domain of unknown function (DUF4210)

RNA

  1. XR_001778884.3 RNA Sequence

  2. XR_379417.5 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q69ZK7.3 GenPept UniProtKB/Swiss-Prot:Q69ZK7

Gene LinkOut

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