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Zfp810 zinc finger protein 810 [ Mus musculus (house mouse) ]

Gene ID: 235050, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp810provided by MGI
Official Full Name
zinc finger protein 810provided by MGI
Primary source
MGI:MGI:2384563
See related
Ensembl:ENSMUSG00000066829 AllianceGenome:MGI:2384563
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Is expressed in early conceptus and genitourinary system. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E14 (RPKM 8.3), whole brain E14.5 (RPKM 7.5) and 28 other tissues See more
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Genomic context

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Location:
9 A3; 9 8.79 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (22188044..22218973, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (22276737..22307814, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1382 Neighboring gene predicted gene, 39307 Neighboring gene predicted gene, 39308 Neighboring gene zinc finger protein 810 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E887 Neighboring gene STARR-seq mESC enhancer starr_23542 Neighboring gene STARR-seq mESC enhancer starr_23543 Neighboring gene high mobility group nucleosomal binding domain 2 pseudogene Neighboring gene 40S ribosomal protein S20 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC6652

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 157

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001409748.1 → NP_001396677.1  zinc finger protein 157 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC159308

  2. NM_001409749.1 → NP_001396678.1  zinc finger protein 157 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC159308

  3. NM_145612.3 → NP_663587.1  zinc finger protein 157 isoform 1

    See identical proteins and their annotated locations for NP_663587.1

    Status: VALIDATED

    Source sequence(s)
    AC159308
    Consensus CDS
    CCDS40562.1
    UniProtKB/TrEMBL
    Q99K45
    Related
    ENSMUSP00000083459.7, ENSMUST00000086278.7
    Conserved Domains (4) summary
    smart00349
    Location:4 → 59
    KRAB; krueppel associated box
    COG5048
    Location:194 → 368
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:324 → 344
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:364 → 387
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. NR_176893.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC159308

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    22188044..22218973 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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