U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Klhl36 kelch-like 36 [ Mus musculus (house mouse) ]

Gene ID: 234796, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Klhl36provided by MGI
Official Full Name
kelch-like 36provided by MGI
Primary source
MGI:MGI:2385305
See related
Ensembl:ENSMUSG00000031828 AllianceGenome:MGI:2385305
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable cullin family protein binding activity. Orthologous to human KLHL36 (kelch like family member 36). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 21.9), kidney adult (RPKM 16.6) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
8 E1; 8 68.52 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (120588970..120603728)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (119862231..119876989)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E113 Neighboring gene MTOR associated protein, eak-7 homolog Neighboring gene coactosin like F-actin binding protein 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:122361795-122361952 Neighboring gene STARR-positive B cell enhancer ABC_E2880 Neighboring gene STARR-positive B cell enhancer mm9_chr8:122367394-122367695 Neighboring gene STARR-positive B cell enhancer ABC_E2881 Neighboring gene predicted gene, 53464 Neighboring gene STARR-positive B cell enhancer mm9_chr8:122434591-122434892 Neighboring gene ubiquitin specific peptidase 10 Neighboring gene STARR-seq mESC enhancer starr_22870

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Little skate genome provides insights into genetic programs essential for limb-based locomotion. Yoo D, et al. Elife, 2022 Oct 26. PMID 36288084, Free PMC Article
  2. Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling. Ling KH, et al. Genome Biol, 2009. PMID 19799774, Free PMC Article
  3. Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Apr 30. PMID 15449545
  4. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC37805

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cullin family protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cullin family protein binding ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
kelch-like protein 36

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146219.1 → NP_666331.1  kelch-like protein 36

    See identical proteins and their annotated locations for NP_666331.1

    Status: PROVISIONAL

    Source sequence(s)
    BC025816
    Consensus CDS
    CCDS22713.1
    UniProtKB/Swiss-Prot
    Q3U0B9, Q6KAS2, Q8R124
    Related
    ENSMUSP00000034287.9, ENSMUST00000034287.10
    Conserved Domains (6) summary
    smart00612
    Location:545 → 591
    Kelch; Kelch domain
    smart00875
    Location:147 → 247
    BACK; BTB And C-terminal Kelch
    PHA03098
    Location:58 → 583
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:333 → 381
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:35 → 138
    BTB; BTB/POZ domain
    pfam01344
    Location:332 → 382
    Kelch_1; Kelch motif

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    120588970..120603728
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001778433.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8R124.1 GenPept UniProtKB/Swiss-Prot:Q8R124

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous