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Zfp961 zinc finger protein 961 [ Mus musculus (house mouse) ]

Gene ID: 234413, updated on 21-Apr-2024

Summary

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Official Symbol
Zfp961provided by MGI
Official Full Name
zinc finger protein 961provided by MGI
Primary source
MGI:MGI:3583954
See related
Ensembl:ENSMUSG00000052446 AllianceGenome:MGI:3583954
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mszf37; BC065788; mszf55-2; A230105L22Rik
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and hemolymphoid system gland. Orthologous to human ZNF101 (zinc finger protein 101). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 6.9), bladder adult (RPKM 6.1) and 28 other tissues See more
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Genomic context

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Location:
8 B3.3; 8 34.63 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (72704910..72724177)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (71951048..71970333)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 882 Neighboring gene STARR-positive B cell enhancer ABC_E10511 Neighboring gene cyclin B2, pseudogene Neighboring gene zinc finger protein 617 Neighboring gene STARR-positive B cell enhancer ABC_E3784 Neighboring gene STARR-seq mESC enhancer starr_21836 Neighboring gene STARR-seq mESC enhancer starr_21837 Neighboring gene STARR-seq mESC enhancer starr_21838 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 18 Neighboring gene predicted gene, 51535 Neighboring gene predicted gene 45734

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC234413

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164581.1 → NP_001158053.1  uncharacterized protein LOC234413

    Status: VALIDATED

    Source sequence(s)
    AC164531
    Consensus CDS
    CCDS52591.1
    UniProtKB/TrEMBL
    E9Q4R5
    Related
    ENSMUSP00000105623.3, ENSMUST00000109997.10
    Conserved Domains (6) summary
    smart00349
    Location:25 → 65
    KRAB; krueppel associated box
    COG5048
    Location:280 → 439
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:340 → 360
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:201 → 221
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:25 → 64
    KRAB; KRAB box
    pfam13465
    Location:380 → 405
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    72704910..72724177
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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