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Prr14 proline rich 14 [ Mus musculus (house mouse) ]

Gene ID: 233895, updated on 5-Mar-2024

Summary

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Official Symbol
Prr14provided by MGI
Official Full Name
proline rich 14provided by MGI
Primary source
MGI:MGI:2384565
See related
Ensembl:ENSMUSG00000030822 AllianceGenome:MGI:2384565
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to act upstream of or within muscle organ development. Predicted to be located in chromosome and nucleus. Predicted to be active in nucleoplasm. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human PRR14 (proline rich 14). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 13.1), adrenal adult (RPKM 8.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
7 F3; 7 69.53 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (127070189..127075932)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127466324..127476767)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_20181 Neighboring gene zinc finger protein 688 Neighboring gene RIKEN cDNA B130055M24 gene Neighboring gene STARR-positive B cell enhancer ABC_E1095 Neighboring gene zinc finger protein 689 Neighboring gene STARR-seq mESC enhancer starr_20182 Neighboring gene STARR-seq mESC enhancer starr_20183 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:134614302-134614485 Neighboring gene STARR-positive B cell enhancer ABC_E1742 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:134621461-134621644 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:134621862-134622045 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:134623956-134624143 Neighboring gene fibrosin Neighboring gene microRNA 7060 Neighboring gene RIKEN cDNA 1700008J07 gene Neighboring gene STARR-seq mESC enhancer starr_20184 Neighboring gene Snf2-related CREBBP activator protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  2. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC6888

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
acts_upstream_of_or_within muscle organ development IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
proline-rich protein 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001416090.1 → NP_001403019.1  proline-rich protein 14

    Status: VALIDATED

    Source sequence(s)
    AC136146
    UniProtKB/Swiss-Prot
    Q7TPN9, Q922N8
    Related
    ENSMUSP00000101899.2, ENSMUST00000106292.8

  2. NM_145589.3 → NP_663564.2  proline-rich protein 14

    See identical proteins and their annotated locations for NP_663564.2

    Status: VALIDATED

    Source sequence(s)
    AC136146
    Consensus CDS
    CCDS21868.1
    UniProtKB/Swiss-Prot
    Q7TPN9, Q922N8
    Related
    ENSMUSP00000033095.9, ENSMUST00000033095.10
    Conserved Domains (2) summary
    PHA03247
    Location:91 → 443
    PHA03247; large tegument protein UL36; Provisional
    pfam15386
    Location:491 → 544
    Tantalus; Drosophila Tantalus-like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    127070189..127075932
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030242535.2 → XP_030098395.1  proline-rich protein 14 isoform X3

    Conserved Domains (1) summary
    pfam15386
    Location:266 → 319
    Tantalus; Drosophila Tantalus-like
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7TPN9.1 GenPept UniProtKB/Swiss-Prot:Q7TPN9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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