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Zfp764 zinc finger protein 764 [ Mus musculus (house mouse) ]

Gene ID: 233893, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp764provided by MGI
Official Full Name
zinc finger protein 764provided by MGI
Primary source
MGI:MGI:2443580
See related
Ensembl:ENSMUSG00000045757 AllianceGenome:MGI:2443580
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
8030466O12Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in early conceptus; genitourinary system; heart; and limb. Orthologous to human ZNF764 (zinc finger protein 764). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in large intestine adult (RPKM 1.7), lung adult (RPKM 1.7) and 28 other tissues See more
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Genomic context

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See Zfp764 in Genome Data Viewer
Location:
7 F3; 7 69.5 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (126975978..127006005, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127379762..127406835, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9710 Neighboring gene ferredoxin 1-like pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E9711 Neighboring gene zinc finger protein 747 Neighboring gene zinc finger protein 747 like 1 Neighboring gene STARR-positive B cell enhancer ABC_E4978 Neighboring gene zinc finger protein 764 like 1 Neighboring gene STARR-positive B cell enhancer ABC_E4979 Neighboring gene SMT3 suppressor of mif two 3 homolog 2, pseudogene 2 (S. cerevisiae) Neighboring gene myeloma-overexpressed gene 2 protein homolog Neighboring gene STARR-seq mESC enhancer starr_20181 Neighboring gene zinc finger protein 688

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  2. An atlas of combinatorial transcriptional regulation in mouse and man. Ravasi T, et al. Cell, 2010 Mar 5. PMID 20211142, Free PMC Article
  3. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  5. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC31213

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription coregulator activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cellular response to glucocorticoid stimulus ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger protein 764

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001167832.1 → NP_001161304.1  zinc finger protein 764 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 5' coding region, compared to variant 1. This difference results in a frameshift and a protein (isoform 2) with a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK042873, AK053795
    UniProtKB/TrEMBL
    Q8C964
    Related
    ENSMUST00000139118.2
    Conserved Domains (1) summary
    pfam01352
    Location:22 → 49
    KRAB; KRAB box

  2. NM_146203.4 → NP_666315.3  zinc finger protein 764 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform 1.
    Source sequence(s)
    AK042873, AK053795
    Consensus CDS
    CCDS21865.1
    UniProtKB/TrEMBL
    E9QAP1, Q8C964
    Related
    ENSMUSP00000052944.7, ENSMUST00000059199.7
    Conserved Domains (6) summary
    smart00349
    Location:22 → 81
    KRAB; krueppel associated box
    COG5048
    Location:178 → 243
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:154 → 174
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:321 → 343
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:22 → 55
    KRAB; KRAB box
    pfam13465
    Location:335 → 360
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    126975978..127006005 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_869713.4 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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