Zfp768 zinc finger protein 768 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp768provided by MGI
Official Full Name: zinc finger protein 768provided by MGI
Primary source: MGI:MGI:2384582
See related: Ensembl:ENSMUSG00000047371 AllianceGenome:MGI:2384582
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Znf768
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including cerebellum external granule cell layer; genitourinary system; neural retina; olfactory epithelium; and skeletal muscle. Orthologous to human ZNF768 (zinc finger protein 768). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in duodenum adult (RPKM 31.6), adrenal adult (RPKM 24.4) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 F3; 7 69.47 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (126941967..126944486, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (127342795..127345314, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific double-stranded DNA binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: zinc finger protein 768

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_146202.1 → NP_666314.1 zinc finger protein 768

See identical proteins and their annotated locations for NP_666314.1

Status: PROVISIONAL

Source sequence(s)

BC026432

Consensus CDS

CCDS21864.1

UniProtKB/Swiss-Prot

Q8R0T2

Related

ENSMUSP00000055374.6, ENSMUST00000060783.7

Conserved Domains (4) summary

COG5048
Location:327 → 532

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:487 → 507

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:541 → 563

zf-C2H2; Zinc finger, C2H2 type

pfam13465
Location:359 → 382

zf-H2C2_2; Zinc-finger double domain