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Hirip3 HIRA interacting protein 3 [ Mus musculus (house mouse) ]

Gene ID: 233876, updated on 21-Apr-2024

Summary

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Official Symbol
Hirip3provided by MGI
Official Full Name
HIRA interacting protein 3provided by MGI
Primary source
MGI:MGI:2142364
See related
Ensembl:ENSMUSG00000042606 AllianceGenome:MGI:2142364
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
B130036O03
Summary
Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in nucleus. Is expressed in central nervous system; genitourinary system; and intestine. Orthologous to human HIRIP3 (HIRA interacting protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 42.6), liver E14 (RPKM 25.5) and 16 other tissues See more
Orthologs
human all
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Genomic context

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Location:
7 F3; 7 69.25 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (126461155..126464549)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (126861929..126865377)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930451I11 gene Neighboring gene double C2, alpha Neighboring gene INO80 complex subunit E Neighboring gene STARR-positive B cell enhancer ABC_E8843 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:134005673-134005856 Neighboring gene TAO kinase 2 Neighboring gene STARR-positive B cell enhancer ABC_E2849 Neighboring gene transmembrane protein 219 Neighboring gene predicted gene, 23445

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. HIRA, a mammalian homologue of Saccharomyces cerevisiae transcriptional co-repressors, interacts with Pax3. Magnaghi P, et al. Nat Genet, 1998 Sep. PMID 9731536
  2. Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator. Maier VK, et al. Mol Cell Proteomics, 2015 Jun. PMID 25680957, Free PMC Article
  3. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  4. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
HIRA-interacting protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001421792.1 → NP_001408721.1  HIRA-interacting protein 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC124505

  2. NM_001421795.1 → NP_001408724.1  HIRA-interacting protein 3 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC124505

  3. NM_001421797.1 → NP_001408726.1  HIRA-interacting protein 3 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC124505

  4. NM_001421799.1 → NP_001408728.1  HIRA-interacting protein 3 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC124505

  5. NM_001421801.1 → NP_001408730.1  HIRA-interacting protein 3 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC124505

  6. NM_172746.4 → NP_766334.1  HIRA-interacting protein 3 isoform 1

    See identical proteins and their annotated locations for NP_766334.1

    Status: VALIDATED

    Source sequence(s)
    AC124505
    Consensus CDS
    CCDS21849.1
    UniProtKB/Swiss-Prot
    Q3TSF3, Q8BLH7
    Related
    ENSMUSP00000035535.4, ENSMUST00000037248.10
    Conserved Domains (1) summary
    smart01082
    Location:529 → 565
    CHZ; Histone chaperone domain CHZ

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    126461155..126464549
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001785541.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BLH7.1 GenPept UniProtKB/Swiss-Prot:Q8BLH7

Gene LinkOut

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