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AI987944 expressed sequence AI987944 [ Mus musculus (house mouse) ]

Gene ID: 233168, updated on 8-Feb-2024

Summary

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Official Symbol
AI987944provided by MGI
Official Full Name
expressed sequence AI987944provided by MGI
Primary source
MGI:MGI:2142079
See related
Ensembl:ENSMUSG00000056383 AllianceGenome:MGI:2142079
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Is expressed in dorsal root ganglion and trigeminal ganglion. Orthologous to human ZNF101 (zinc finger protein 101). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 3.3), bladder adult (RPKM 2.9) and 28 other tissues See more
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Genomic context

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Location:
7 B3; 7 28.25 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (41022347..41042772, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (41372923..41393379, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene baculoviral IAP repeat-containing 4 pseudogene Neighboring gene zinc finger, MYND-type containing 8 pseudogene 2 Neighboring gene STARR-positive B cell enhancer ABC_E3715 Neighboring gene predicted gene 17102 Neighboring gene vomeronasal 2, receptor 57 Neighboring gene STARR-seq mESC enhancer starr_18727 Neighboring gene STARR-seq mESC enhancer starr_18728

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  2. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC60751, MGC117553

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC233168

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199330.2 → NP_001186259.1  uncharacterized protein LOC233168 isoform 2

    See identical proteins and their annotated locations for NP_001186259.1

    Status: VALIDATED

    Source sequence(s)
    AC137152
    Consensus CDS
    CCDS85272.1
    UniProtKB/TrEMBL
    Q4KL68
    Related
    ENSMUSP00000145621.2, ENSMUST00000205338.2
    Conserved Domains (3) summary
    COG5048
    Location:48 → 402
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:264 → 284
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1 → 41
    KRAB; KRAB box

  2. NM_001421750.1 → NP_001408679.1  uncharacterized protein LOC233168 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC137152
    UniProtKB/TrEMBL
    Q4KL68

  3. NM_001421752.1 → NP_001408681.1  uncharacterized protein LOC233168 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC137152
    UniProtKB/TrEMBL
    Q4KL68

  4. NM_001421753.1 → NP_001408682.1  uncharacterized protein LOC233168 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC137152

  5. NM_001421754.1 → NP_001408683.1  uncharacterized protein LOC233168 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC137152

  6. NM_001421755.1 → NP_001408684.1  uncharacterized protein LOC233168 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC137152
    UniProtKB/TrEMBL
    A0A0U1RNH4

  7. NM_001421756.1 → NP_001408685.1  uncharacterized protein LOC233168 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC137152

  8. NM_001421757.1 → NP_001408686.1  uncharacterized protein LOC233168 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC137152

  9. NM_183167.5 → NP_898990.1  uncharacterized protein LOC233168 isoform 1

    See identical proteins and their annotated locations for NP_898990.1

    Status: VALIDATED

    Source sequence(s)
    AC137152
    Consensus CDS
    CCDS39920.1
    UniProtKB/TrEMBL
    Q7TPX5
    Related
    ENSMUSP00000071708.8, ENSMUST00000071804.10
    Conserved Domains (5) summary
    smart00349
    Location:4 → 45
    KRAB; krueppel associated box
    COG5048
    Location:51 → 405
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:267 → 287
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4 → 43
    KRAB; KRAB box
    pfam13465
    Location:307 → 332
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. NR_185325.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC137152

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    41022347..41042772 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011250853.3 → XP_011249155.1  uncharacterized protein LOC233168 isoform X1

    See identical proteins and their annotated locations for XP_011249155.1

    UniProtKB/TrEMBL
    Q4KL68
    Conserved Domains (3) summary
    COG5048
    Location:48 → 402
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:264 → 284
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1 → 41
    KRAB; KRAB box
Nucleotide Protein Strain
Heading Accession and Version

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