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Phldb3 pleckstrin homology like domain, family B, member 3 [ Mus musculus (house mouse) ]

Gene ID: 232970, updated on 5-Mar-2024

Summary

Official Symbol
Phldb3provided by MGI
Official Full Name
pleckstrin homology like domain, family B, member 3provided by MGI
Primary source
MGI:MGI:3642959
See related
Ensembl:ENSMUSG00000074277 AllianceGenome:MGI:3642959
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm10102; EG232970
Summary
Predicted to enable enzyme binding activity. Orthologous to human PHLDB3 (pleckstrin homology like domain family B member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in placenta adult (RPKM 3.5), stomach adult (RPKM 3.2) and 20 other tissues See more
Orthologs
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Genomic context

Location:
7 A3; 7 11.8 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (24309731..24328722)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (24610294..24629297)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18269 Neighboring gene X-ray repair complementing defective repair in Chinese hamster cells 1 Neighboring gene zinc finger protein 575 Neighboring gene ethylmalonic encephalopathy 1 Neighboring gene STARR-seq mESC enhancer starr_18271 Neighboring gene STARR-positive B cell enhancer ABC_E4903 Neighboring gene predicted gene, 26550 Neighboring gene Ly6/Plaur domain containing 3 Neighboring gene predicted gene 4598

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
pleckstrin homology-like domain family B member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001102613.1NP_001096083.1  pleckstrin homology-like domain family B member 3

    See identical proteins and their annotated locations for NP_001096083.1

    Status: PROVISIONAL

    Source sequence(s)
    AC161166
    Consensus CDS
    CCDS52139.1
    UniProtKB/TrEMBL
    E9QAF4
    Related
    ENSMUSP00000073047.6, ENSMUST00000073325.6
    Conserved Domains (2) summary
    cd14673
    Location:543643
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:112326
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    24309731..24328722
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017322157.3XP_017177646.1  pleckstrin homology-like domain family B member 3 isoform X2

    UniProtKB/TrEMBL
    E9QAF4
    Conserved Domains (2) summary
    cd14673
    Location:543643
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    TIGR02168
    Location:112326
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  2. XM_030242440.2XP_030098300.1  pleckstrin homology-like domain family B member 3 isoform X1

    Conserved Domains (1) summary
    TIGR02168
    Location:112326
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  3. XM_030242441.2XP_030098301.1  pleckstrin homology-like domain family B member 3 isoform X1

    Conserved Domains (1) summary
    TIGR02168
    Location:112326
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type