U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp954 zinc finger protein 954 [ Mus musculus (house mouse) ]

Gene ID: 232853, updated on 8-Feb-2024

Summary

Go to the top of the page Help
Official Symbol
Zfp954provided by MGI
Official Full Name
zinc finger protein 954provided by MGI
Primary source
MGI:MGI:1917764
See related
Ensembl:ENSMUSG00000062116 AllianceGenome:MGI:1917764
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
8030437F07; 5730403M16Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in early conceptus; genitourinary system; nervous system; and sensory organ. Orthologous to human ZNF419 (zinc finger protein 419) and ZNF773 (zinc finger protein 773). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 6.2), large intestine adult (RPKM 5.6) and 28 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Zfp954 in Genome Data Viewer
Location:
7 A1; 7 4.13 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (7117682..7124475, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (7114683..7121476, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene ARP2 actin-related protein 2 homolog pseudogene Neighboring gene zinc finger protein 954 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E2222 Neighboring gene STARR-seq mESC enhancer starr_18003 Neighboring gene zinc finger protein 773 Neighboring gene STARR-seq mESC enhancer starr_18004 Neighboring gene STARR-seq mESC enhancer starr_18005 Neighboring gene vomeronasal 2, receptor, pseudogene 35

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein LOC232853

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172738.3 → NP_766326.2  uncharacterized protein LOC232853

    See identical proteins and their annotated locations for NP_766326.2

    Status: VALIDATED

    Source sequence(s)
    AK033116, BC055688, BY124760, BY626368
    Consensus CDS
    CCDS51991.1
    UniProtKB/TrEMBL
    Q7TNU5
    Related
    ENSMUSP00000072585.4, ENSMUST00000056246.8
    Conserved Domains (6) summary
    smart00349
    Location:42 → 95
    KRAB; krueppel associated box
    COG5048
    Location:252 → 387
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:200 → 220
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:364 → 386
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:42 → 81
    KRAB; KRAB box
    pfam13465
    Location:241 → 265
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    7117682..7124475 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous