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Lncpint long non-protein coding RNA, Trp53 induced transcript [ Mus musculus (house mouse) ]

Gene ID: 232685, updated on 5-Mar-2024

Summary

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Official Symbol
Lncpintprovided by MGI
Official Full Name
long non-protein coding RNA, Trp53 induced transcriptprovided by MGI
Primary source
MGI:MGI:2673128
See related
Ensembl:ENSMUSG00000044471 AllianceGenome:MGI:2673128
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pint; Lincpint; MNCb-1768; linc-Pint
Summary
Acts upstream of or within several processes, including adipose tissue development; adult somatic muscle development; and hair follicle development. Orthologous to human LINC-PINT (long intergenic non-protein coding RNA, p53 induced transcript). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in lung adult (RPKM 1.5), adrenal adult (RPKM 1.4) and 19 other tissues See more
Orthologs
human all
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Genomic context

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Location:
6 A3.3; 6 12.56 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (31070498..31195409, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (31093563..31218474, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene microRNA 29b-1 Neighboring gene microRNA 29a Neighboring gene STARR-seq mESC enhancer starr_15479 Neighboring gene STARR-positive B cell enhancer ABC_E11314 Neighboring gene STARR-positive B cell enhancer ABC_E6423 Neighboring gene STARR-positive B cell enhancer mm9_chr6:31119400-31119700 Neighboring gene STARR-positive B cell enhancer ABC_E8097 Neighboring gene proteasome (prosome, macropain) subunit, alpha type 3 pseudogene Neighboring gene STARR-seq mESC enhancer starr_15481 Neighboring gene RIKEN cDNA 2210408F21 gene Neighboring gene STARR-seq mESC enhancer starr_15482 Neighboring gene STARR-seq mESC enhancer starr_15483 Neighboring gene STARR-positive B cell enhancer ABC_E4819 Neighboring gene predicted gene, 38782 Neighboring gene STARR-seq mESC enhancer starr_15487 Neighboring gene muskelin 1, intracellular mediator containing kelch motifs, opposite strand Neighboring gene muskelin 1, intracellular mediator containing kelch motifs

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Inhibition of Lincpint expression affects insulin secretion and apoptosis in mouse pancreatic β cells. Zhu Y, et al. Int J Biochem Cell Biol, 2018 Nov. PMID 30201298
  2. A lncRNA survey finds increases in neuroprotective LINC-PINT in Parkinson's disease substantia nigra. Simchovitz A, et al. Aging Cell, 2020 Mar. PMID 32080970, Free PMC Article
  3. Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2. Marín-Béjar O, et al. Genome Biol, 2013. PMID 24070194, Free PMC Article
  4. Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs. Lai KM, et al. PLoS One, 2015. PMID 25909911, Free PMC Article
  5. Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Sauvageau M, et al. Elife, 2013 Dec 31. PMID 24381249, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A lncRNA survey finds increases in neuroprotective LINC-PINT in Parkinson's disease substantia nigra.
    Title: A lncRNA survey finds increases in neuroprotective LINC-PINT in Parkinson's disease substantia nigra.
  2. Inhibition of Lincpint expression affects insulin secretion and apoptosis in mouse pancreatic beta cells
    Title: Inhibition of Lincpint expression affects insulin secretion and apoptosis in mouse pancreatic β cells.
  3. Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2.
    Title: Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Markers

Homology

Other Names

  • long intergenic non-protein coding RNA, Trp53 induced transcript
  • long intergenic non-protein coding RNA, p53 induced transcript

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within adipose tissue development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in adipose tissue development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within adult somatic muscle development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in bone mineralization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within hair follicle development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in hair follicle development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within multicellular organism growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in multicellular organism growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in skeletal muscle fiber development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within skeletal system development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in skeletal system development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within skin development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in tissue development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_110469.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (A) represents the longest transcript.
    Source sequence(s)
    AC024913, AC153820

  2. NR_110470.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (B) lacks an alternate internal exon, resulting in a shorter transcript, compared to variant A.
    Source sequence(s)
    AC024913, AC153820
    Related
    ENSMUST00000231007.3

  3. NR_110471.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (C) lacks two alternate internal exons and differs in the 3' exon structure, resulting in a shorter transcript, compared to variant A.
    Source sequence(s)
    AC024913, AC153820
    Related
    ENSMUST00000187876.7

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    31070498..31195409 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_144555.1: Suppressed sequence

    Description
    NM_144555.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.