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Ccdc174 coiled-coil domain containing 174 [ Mus musculus (house mouse) ]

Gene ID: 232236, updated on 5-Mar-2024

Summary

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Official Symbol
Ccdc174provided by MGI
Official Full Name
coiled-coil domain containing 174provided by MGI
Primary source
MGI:MGI:2444652
See related
Ensembl:ENSMUSG00000034083 AllianceGenome:MGI:2444652
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C130022K22Rik
Summary
Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human CCDC174 (coiled-coil domain containing 174). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 7.0), CNS E14 (RPKM 4.7) and 27 other tissues See more
Orthologs
human all
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Genomic context

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Location:
6 D1; 6 40.9 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (91819983..91876830)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (91843154..91899849)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:91629122-91629420 Neighboring gene predicted gene, 40387 Neighboring gene predicted gene, 30628 Neighboring gene STARR-seq mESC enhancer starr_16652 Neighboring gene solute carrier family 6 (neurotransmitter transporter, taurine), member 6 Neighboring gene STARR-seq mESC enhancer starr_16656 Neighboring gene STARR-seq mESC enhancer starr_16660 Neighboring gene glutamate receptor interacting protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E6456 Neighboring gene RIKEN cDNA 4930590J08 gene Neighboring gene predicted gene, 53299

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Transgenic (1) 
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 174

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172730.2 → NP_766318.2  coiled-coil domain-containing protein 174

    See identical proteins and their annotated locations for NP_766318.2

    Status: VALIDATED

    Source sequence(s)
    AC168852, AK039818, BC051147, BY624970
    Consensus CDS
    CCDS20370.2
    UniProtKB/Swiss-Prot
    Q3U155, Q80XC8, Q8CA20
    UniProtKB/TrEMBL
    A0A0R4J0L8
    Related
    ENSMUSP00000049280.6, ENSMUST00000037783.7
    Conserved Domains (2) summary
    PTZ00121
    Location:3 → 329
    PTZ00121; MAEBL; Provisional
    pfam13300
    Location:230 → 303
    DUF4078; Domain of unknown function (DUF4078)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    91819983..91876830
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030255347.2 → XP_030111207.1  coiled-coil domain-containing protein 174 isoform X1

    UniProtKB/Swiss-Prot
    Q3U155, Q80XC8, Q8CA20
    UniProtKB/TrEMBL
    A0A0R4J0L8
    Conserved Domains (2) summary
    PTZ00121
    Location:3 → 329
    PTZ00121; MAEBL; Provisional
    pfam13300
    Location:230 → 303
    DUF4078; Domain of unknown function (DUF4078)

  2. XM_036166055.1 → XP_036021948.1  coiled-coil domain-containing protein 174 isoform X1

    UniProtKB/Swiss-Prot
    Q3U155, Q80XC8, Q8CA20
    UniProtKB/TrEMBL
    A0A0R4J0L8
    Conserved Domains (2) summary
    PTZ00121
    Location:3 → 329
    PTZ00121; MAEBL; Provisional
    pfam13300
    Location:230 → 303
    DUF4078; Domain of unknown function (DUF4078)

  3. XM_036166056.1 → XP_036021949.1  coiled-coil domain-containing protein 174 isoform X2

    UniProtKB/Swiss-Prot
    Q3U155, Q80XC8, Q8CA20
    Conserved Domains (2) summary
    PTZ00121
    Location:3 → 328
    PTZ00121; MAEBL; Provisional
    pfam13300
    Location:230 → 303
    DUF4078; Domain of unknown function (DUF4078)

  4. XM_030255348.2 → XP_030111208.1  coiled-coil domain-containing protein 174 isoform X3

    UniProtKB/TrEMBL
    Q8C4Q1
    Conserved Domains (1) summary
    pfam13300
    Location:122 → 195
    DUF4078; Domain of unknown function (DUF4078)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3U155.1 GenPept UniProtKB/Swiss-Prot:Q3U155

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