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Galnt9 polypeptide N-acetylgalactosaminyltransferase 9 [ Mus musculus (house mouse) ]

Gene ID: 231605, updated on 30-Apr-2024

Summary

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Official Symbol
Galnt9provided by MGI
Official Full Name
polypeptide N-acetylgalactosaminyltransferase 9provided by MGI
Primary source
MGI:MGI:2677965
See related
Ensembl:ENSMUSG00000033316 AllianceGenome:MGI:2677965
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GalNAc-T9
Summary
Predicted to be active in Golgi apparatus. Is expressed in several structures, including integumental system; limb; nervous system; and sensory organ. Orthologous to human GALNT9 (polypeptide N-acetylgalactosaminyltransferase 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cerebellum adult (RPKM 21.5), cortex adult (RPKM 19.3) and 6 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 F; 5 53.66 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (110692217..110769244)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (110544032..110621383)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32996 Neighboring gene RIKEN cDNA A630023P12 gene Neighboring gene STARR-seq mESC enhancer starr_13961 Neighboring gene NOC4 like Neighboring gene DEAD box helicase 51

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex. Molyneaux BJ, et al. Neuron, 2015 Jan 21. PMID 25556833, Free PMC Article
  2. Loss of the disease-associated glycosyltransferase Galnt3 alters Muc10 glycosylation and the composition of the oral microbiome. Peluso G, et al. J Biol Chem, 2020 Jan 31. PMID 31882545, Free PMC Article
  3. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

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Markers

Homology

Clone Names

  • 6430598F23

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables polypeptide N-acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
polypeptide N-acetylgalactosaminyltransferase 9
Names
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
NP_001116111.1
NP_938048.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001122639.3 → NP_001116111.1  polypeptide N-acetylgalactosaminyltransferase 9 isoform B

    See identical proteins and their annotated locations for NP_001116111.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (B) lacks several exons, contains an alternate 5' terminal exon and initiates translation at a downstream start codon, compared to variant A. It encodes isoform B, which is shorter at the N-terminus, compared to isoform A.
    Source sequence(s)
    AC161231, AC161348
    Consensus CDS
    CCDS51611.1
    UniProtKB/TrEMBL
    Q3TB05
    Related
    ENSMUSP00000133111.2, ENSMUST00000165856.3
    Conserved Domains (3) summary
    cd00161
    Location:100 → 228
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:98 → 226
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
    cl11394
    Location:1 → 87
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

  2. NM_198306.4 → NP_938048.2  polypeptide N-acetylgalactosaminyltransferase 9 isoform A

    See identical proteins and their annotated locations for NP_938048.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (A) represents the longest transcript and encodes the longer isoform (A).
    Source sequence(s)
    AC161231, AC161348
    Consensus CDS
    CCDS51610.1
    UniProtKB/TrEMBL
    G3X942
    Related
    ENSMUSP00000038633.8, ENSMUST00000040001.14
    Conserved Domains (3) summary
    cd02510
    Location:155 → 454
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    cd00161
    Location:467 → 595
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:465 → 593
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

RNA

  1. NR_104449.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (C) lacks several exons, contains an alternate 5' terminal exon and uses an alternate splice site in a 3' exon, compared to variant A. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant B, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC161231, AC161348
    Related
    ENSMUST00000200404.5

  2. NR_185192.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC161231, AC161348

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    110692217..110769244
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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