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Haus3 HAUS augmin-like complex, subunit 3 [ Mus musculus (house mouse) ]

Gene ID: 231123, updated on 2-Apr-2024

Summary

Official Symbol
Haus3provided by MGI
Official Full Name
HAUS augmin-like complex, subunit 3provided by MGI
Primary source
MGI:MGI:2387633
See related
Ensembl:ENSMUSG00000079555 AllianceGenome:MGI:2387633
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D4S43h; D5H4S43; D5H4S43E
Summary
Predicted to be involved in centrosome cycle and spindle assembly. Predicted to act upstream of or within cell division. Predicted to be located in several cellular components, including intercellular bridge; mitotic spindle microtubule; and nucleoplasm. Predicted to be part of HAUS complex. Predicted to be active in centrosome and mitotic spindle. Is expressed in brain ventricular layer; paravertebral ganglion; renal cortex; and thymus primordium. Orthologous to human HAUS3 (HAUS augmin like complex subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E11.5 (RPKM 12.2), liver E14 (RPKM 7.4) and 14 other tissues See more
Orthologs
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Genomic context

See Haus3 in Genome Data Viewer
Location:
5 B2; 5 17.84 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (34311240..34326768, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (34153896..34169424, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene N-acetyltransferase 8-like Neighboring gene DNA polymerase N Neighboring gene STARR-seq mESC enhancer starr_12835 Neighboring gene RIKEN cDNA 4930557J02 gene Neighboring gene STARR-positive B cell enhancer ABC_E1299 Neighboring gene STARR-seq mESC enhancer starr_12836 Neighboring gene predicted gene, 25918 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:34530746-34530855 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:34537815-34537924 Neighboring gene Max dimerization protein 4 Neighboring gene zinc finger, FYVE domain containing 28 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:34575558-34575759 Neighboring gene cilia and flagella associated protein 99

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • MGC36997, MGC38108, MGC38583

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in centrosome cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in centrosome cycle ISO
Inferred from Sequence Orthology
more info
 
involved_in spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in spindle assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of HAUS complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of HAUS complex ISO
Inferred from Sequence Orthology
more info
 
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitotic spindle IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitotic spindle microtubule ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
HAUS augmin-like complex subunit 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146159.2NP_666271.1  HAUS augmin-like complex subunit 3

    See identical proteins and their annotated locations for NP_666271.1

    Status: VALIDATED

    Source sequence(s)
    AC157989
    Consensus CDS
    CCDS19211.1
    UniProtKB/Swiss-Prot
    Q3TSW5, Q8BQL2, Q8CIH1, Q8QZX2
    Related
    ENSMUSP00000049973.7, ENSMUST00000060049.8
    Conserved Domains (1) summary
    pfam14932
    Location:29281
    HAUS-augmin3; HAUS augmin-like complex subunit 3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    34311240..34326768 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)