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Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 [ Mus musculus (house mouse) ]

Gene ID: 230861, updated on 5-Mar-2024

Summary

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Official Symbol
Eif4g3provided by MGI
Official Full Name
eukaryotic translation initiation factor 4 gamma, 3provided by MGI
Primary source
MGI:MGI:1923935
See related
Ensembl:ENSMUSG00000028760 AllianceGenome:MGI:1923935
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
repro8; Gm32394; eIF4GII; G1-419-52; 1500002J22Rik; 4930523M17Rik
Summary
Predicted to enable mRNA binding activity and translation initiation factor activity. Acts upstream of or within positive regulation of cellular protein metabolic process; positive regulation of meiosis I; and spermatogenesis. Predicted to be part of eukaryotic translation initiation factor 4F complex. Is expressed in nervous system; neural retina; and submandibular gland primordium. Orthologous to human EIF4G3 (eukaryotic translation initiation factor 4 gamma 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 43.2), CNS E11.5 (RPKM 29.8) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
4; 4 D3
Exon count:
41
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (137719090..137934397)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (137991779..138207086)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_11797 Neighboring gene endothelin converting enzyme 1 Neighboring gene predicted gene 13012 Neighboring gene predicted gene, 52683 Neighboring gene STARR-positive B cell enhancer mm9_chr4:137508798-137509099 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:137524336-137524519 Neighboring gene STARR-positive B cell enhancer mm9_chr4:137549212-137549513 Neighboring gene STARR-seq mESC enhancer starr_11798 Neighboring gene STARR-positive B cell enhancer ABC_E6242 Neighboring gene RIKEN cDNA 1700095J12 gene Neighboring gene microRNA 6399 Neighboring gene heterochromatin protein 1, binding protein 3 Neighboring gene SH2 domain containing 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions. Gonatopoulos-Pournatzis T, et al. Mol Cell, 2020 Mar 19. PMID 31999954
  2. Reduced DEAF1 function during type 1 diabetes inhibits translation in lymph node stromal cells by suppressing Eif4g3. Yip L, et al. J Mol Cell Biol, 2013 Apr. PMID 22923498, Free PMC Article
  3. Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes. Sun F, et al. Development, 2010 May. PMID 20430745, Free PMC Article
  4. Alcohol and indinavir adversely affect protein synthesis and phosphorylation of MAPK and mTOR signaling pathways in C2C12 myocytes. Hong-Brown LQ, et al. Alcohol Clin Exp Res, 2006 Aug. PMID 16899032
  5. Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice. Hu J, et al. Biol Reprod, 2018 Jan 1. PMID 29161344, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The results of this study showed that EIF4G3 is located in the nucleus of spermatocytes, where it is highly enriched in the XY body, the chromatin domain formed by the transcriptionally inactive sex chromosomes.
    Title: Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice.
  2. reduced DEAF1 function, and subsequent loss of Eif4g3 transcription may affect peripheral tissue antigen (PTA) expression in LNSCs and contribute to the pathology of T1D.
    Title: Reduced DEAF1 function during type 1 diabetes inhibits translation in lymph node stromal cells by suppressing Eif4g3.
  3. EIF4G3 is required for HSPA2 translation in spermatocytes and mutations can cause male infertility.
    Title: Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (3)  1 citation
  • Chemically induced (ENU) (1) 
  • Endonuclease-mediated (1)  1 citation

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • 4833436O05

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables translation initiation factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of meiosis I IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within positive regulation of protein phosphorylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of translation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within positive regulation of translation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of translation IEA
Inferred from Electronic Annotation
more info
  
involved_in spermatid development IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within spermatogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of translation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translational initiation NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of eukaryotic translation initiation factor 4F complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of eukaryotic translation initiation factor 4F complex NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in intracellular non-membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
 PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
eukaryotic translation initiation factor 4 gamma 3
Names
eIF-4-gamma 3
eIF-4-gamma II

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256195.1 → NP_001243124.1  eukaryotic translation initiation factor 4 gamma 3 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR and lacks an alternate, in-frame, exon in the 5' coding region, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1.
    Source sequence(s)
    AK019693, BC079885, BE852849, CX566741
    UniProtKB/TrEMBL
    Z4YKC4
    Related
    ENSMUSP00000101457.3, ENSMUST00000105831.9
    Conserved Domains (5) summary
    cd11559
    Location:1406 → 1538
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    pfam02847
    Location:1204 → 1316
    MA3; MA3 domain
    pfam02854
    Location:757 → 985
    MIF4G; MIF4G domain
    pfam11235
    Location:171 → 331
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    cl17013
    Location:1517 → 1563
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  2. NM_001256198.1 → NP_001243127.1  eukaryotic translation initiation factor 4 gamma 3 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains an alternate exon in the 5' UTR and lacks an alternate, in-frame, exon in the 3' coding region which causes a shift in the reading frame, compared to variant 1. The resulting protein (isoform 3) has a shorter and distinct C-terminus when it is compared to isoform 1.
    Source sequence(s)
    AK019693, BC082549, BE852849, CX566741
    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (2) summary
    pfam02847
    Location:1223 → 1335
    MA3; MA3 domain
    pfam02854
    Location:757 → 985
    MIF4G; MIF4G domain

  3. NM_001355699.1 → NP_001342628.1  eukaryotic translation initiation factor 4 gamma 3 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AK029440, AL807747, BE852849, CX566741
    UniProtKB/TrEMBL
    Z4YKC4
    Conserved Domains (5) summary
    cd11559
    Location:1448 → 1580
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    pfam02847
    Location:1246 → 1358
    MA3; MA3 domain
    pfam02854
    Location:799 → 1027
    MIF4G; MIF4G domain
    cl17013
    Location:1559 → 1605
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon
    cl26386
    Location:210 → 374
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  4. NM_001355700.1 → NP_001342629.1  eukaryotic translation initiation factor 4 gamma 3 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AK029440, AL807747, BE852849, CX566741
    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (4) summary
    cd11559
    Location:1169 → 1301
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    pfam02847
    Location:967 → 1079
    MA3; MA3 domain
    pfam02854
    Location:501 → 729
    MIF4G; MIF4G domain
    cl17013
    Location:1280 → 1326
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  5. NM_001369130.1 → NP_001356059.1  eukaryotic translation initiation factor 4 gamma 3 isoform 6

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) encodes the longest isoform (6).
    Source sequence(s)
    AL807747, AL929388
    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1456 → 1588
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:4 → 369
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1254 → 1366
    MA3; MA3 domain
    pfam02854
    Location:788 → 1016
    MIF4G; MIF4G domain
    pfam11235
    Location:202 → 362
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    cl17013
    Location:1567 → 1613
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  6. NM_001369131.1 → NP_001356060.1  eukaryotic translation initiation factor 4 gamma 3 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AK046639, AL807747
    Consensus CDS
    CCDS89847.1
    UniProtKB/TrEMBL
    Q8BQR8
    Related
    ENSMUSP00000059465.4, ENSMUST00000058133.10
    Conserved Domains (1) summary
    PRK14954
    Location:153 → 235
    PRK14954; DNA polymerase III subunits gamma and tau; Provisional

  7. NM_172703.3 → NP_766291.2  eukaryotic translation initiation factor 4 gamma 3 isoform 1

    See identical proteins and their annotated locations for NP_766291.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    BC072600, BE852849, BY310944, CX566741
    Consensus CDS
    CCDS38926.1
    UniProtKB/TrEMBL
    A0A0R4J112, Z4YKC4
    Related
    ENSMUSP00000081232.6, ENSMUST00000084214.12
    Conserved Domains (4) summary
    cd11559
    Location:1417 → 1549
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    pfam02847
    Location:1215 → 1327
    MA3; MA3 domain
    pfam02854
    Location:768 → 996
    MIF4G; MIF4G domain
    cl17013
    Location:1528 → 1574
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

RNA

  1. NR_161160.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL807747

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    137719090..137934397
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006538776.4 → XP_006538839.1  eukaryotic translation initiation factor 4 gamma 3 isoform X1

    UniProtKB/TrEMBL
    A0A0N4SVL0
    Conserved Domains (5) summary
    cd11559
    Location:1612 → 1744
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:57 → 472
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1410 → 1522
    MA3; MA3 domain
    pfam02854
    Location:944 → 1172
    MIF4G; MIF4G domain
    cl17013
    Location:1723 → 1769
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  2. XM_006538779.4 → XP_006538842.1  eukaryotic translation initiation factor 4 gamma 3 isoform X3

    UniProtKB/TrEMBL
    A0A0N4SVL0
    Conserved Domains (5) summary
    cd11559
    Location:1585 → 1717
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:57 → 476
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1383 → 1495
    MA3; MA3 domain
    pfam02854
    Location:917 → 1145
    MIF4G; MIF4G domain
    cl17013
    Location:1696 → 1742
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  3. XM_036164070.1 → XP_036019963.1  eukaryotic translation initiation factor 4 gamma 3 isoform X11

    UniProtKB/TrEMBL
    A0A0N4SVL0
    Conserved Domains (5) summary
    cd11559
    Location:1566 → 1698
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:57 → 476
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1364 → 1476
    MA3; MA3 domain
    pfam02854
    Location:917 → 1145
    MIF4G; MIF4G domain
    cl17013
    Location:1677 → 1723
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  4. XM_030253471.1 → XP_030109331.1  eukaryotic translation initiation factor 4 gamma 3 isoform X4

    UniProtKB/TrEMBL
    A0A0N4SVL0
    Conserved Domains (5) summary
    cd11559
    Location:1584 → 1716
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:57 → 475
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1382 → 1494
    MA3; MA3 domain
    pfam02854
    Location:916 → 1144
    MIF4G; MIF4G domain
    cl17013
    Location:1695 → 1741
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  5. XM_017320166.2 → XP_017175655.1  eukaryotic translation initiation factor 4 gamma 3 isoform X5

    UniProtKB/TrEMBL
    A0A0N4SVL0
    Conserved Domains (5) summary
    cd11559
    Location:1581 → 1713
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:57 → 472
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1379 → 1491
    MA3; MA3 domain
    pfam02854
    Location:913 → 1141
    MIF4G; MIF4G domain
    cl17013
    Location:1692 → 1738
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  6. XM_017320167.2 → XP_017175656.1  eukaryotic translation initiation factor 4 gamma 3 isoform X7

    UniProtKB/TrEMBL
    A0A0N4SVL0
    Related
    ENSMUSP00000159837.1, ENSMUST00000249658.1
    Conserved Domains (5) summary
    cd11559
    Location:1574 → 1706
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:57 → 465
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1372 → 1484
    MA3; MA3 domain
    pfam02854
    Location:906 → 1134
    MIF4G; MIF4G domain
    cl17013
    Location:1685 → 1731
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  7. XM_036164071.1 → XP_036019964.1  eukaryotic translation initiation factor 4 gamma 3 isoform X12

    UniProtKB/TrEMBL
    A0A0N4SVL0
    Conserved Domains (5) summary
    cd11559
    Location:1555 → 1687
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:57 → 465
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1353 → 1465
    MA3; MA3 domain
    pfam02854
    Location:906 → 1134
    MIF4G; MIF4G domain
    cl17013
    Location:1666 → 1712
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  8. XM_030253473.2 → XP_030109333.1  eukaryotic translation initiation factor 4 gamma 3 isoform X8

    UniProtKB/TrEMBL
    A0A0N4SVL0
    Conserved Domains (5) summary
    cd11559
    Location:1573 → 1705
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:57 → 464
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1371 → 1483
    MA3; MA3 domain
    pfam02854
    Location:905 → 1133
    MIF4G; MIF4G domain
    cl17013
    Location:1684 → 1730
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  9. XM_036164068.1 → XP_036019961.1  eukaryotic translation initiation factor 4 gamma 3 isoform X2

    UniProtKB/TrEMBL
    A0A0N4SVL0
    Conserved Domains (5) summary
    cd11559
    Location:1605 → 1737
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:57 → 518
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1403 → 1515
    MA3; MA3 domain
    pfam02854
    Location:937 → 1165
    MIF4G; MIF4G domain
    cl17013
    Location:1716 → 1762
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  10. XM_030253472.2 → XP_030109332.1  eukaryotic translation initiation factor 4 gamma 3 isoform X6

    UniProtKB/TrEMBL
    A0A0N4SVL0
    Conserved Domains (5) summary
    cd11559
    Location:1578 → 1710
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:62 → 491
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1376 → 1488
    MA3; MA3 domain
    pfam02854
    Location:910 → 1138
    MIF4G; MIF4G domain
    cl17013
    Location:1689 → 1735
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  11. XM_030253474.1 → XP_030109334.1  eukaryotic translation initiation factor 4 gamma 3 isoform X10

    UniProtKB/TrEMBL
    A0A0N4SVL0
    Conserved Domains (5) summary
    cd11559
    Location:1567 → 1699
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:57 → 480
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1365 → 1477
    MA3; MA3 domain
    pfam02854
    Location:899 → 1127
    MIF4G; MIF4G domain
    cl17013
    Location:1678 → 1724
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  12. XM_036164069.1 → XP_036019962.1  eukaryotic translation initiation factor 4 gamma 3 isoform X9

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (5) summary
    cd11559
    Location:1569 → 1701
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:62 → 482
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1367 → 1479
    MA3; MA3 domain
    pfam02854
    Location:901 → 1129
    MIF4G; MIF4G domain
    cl17013
    Location:1680 → 1726
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  13. XM_030253475.1 → XP_030109335.1  eukaryotic translation initiation factor 4 gamma 3 isoform X13

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (5) summary
    cd11559
    Location:1542 → 1674
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:57 → 449
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1340 → 1452
    MA3; MA3 domain
    pfam02854
    Location:874 → 1102
    MIF4G; MIF4G domain
    cl17013
    Location:1653 → 1699
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  14. XM_036164073.1 → XP_036019966.1  eukaryotic translation initiation factor 4 gamma 3 isoform X18

    UniProtKB/TrEMBL
    Z4YKC4
    Conserved Domains (5) summary
    cd11559
    Location:1523 → 1655
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:57 → 449
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1321 → 1433
    MA3; MA3 domain
    pfam02854
    Location:874 → 1102
    MIF4G; MIF4G domain
    cl17013
    Location:1634 → 1680
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  15. XM_036164072.1 → XP_036019965.1  eukaryotic translation initiation factor 4 gamma 3 isoform X14

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (5) summary
    cd11559
    Location:1541 → 1673
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:62 → 454
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1339 → 1451
    MA3; MA3 domain
    pfam02854
    Location:873 → 1101
    MIF4G; MIF4G domain
    cl17013
    Location:1652 → 1698
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  16. XM_036164083.1 → XP_036019976.1  eukaryotic translation initiation factor 4 gamma 3 isoform X32

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (4) summary
    cd11559
    Location:1169 → 1301
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    pfam02847
    Location:967 → 1079
    MA3; MA3 domain
    pfam02854
    Location:501 → 729
    MIF4G; MIF4G domain
    cl17013
    Location:1280 → 1326
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  17. XM_006538785.4 → XP_006538848.1  eukaryotic translation initiation factor 4 gamma 3 isoform X15

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1538 → 1670
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:57 → 445
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1336 → 1448
    MA3; MA3 domain
    pfam02854
    Location:870 → 1098
    MIF4G; MIF4G domain
    pfam09770
    Location:57 → 197
    PAT1; Topoisomerase II-associated protein PAT1
    cl17013
    Location:1649 → 1695
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  18. XM_030253476.1 → XP_030109336.1  eukaryotic translation initiation factor 4 gamma 3 isoform X16

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (5) summary
    cd11559
    Location:1531 → 1663
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    pfam02847
    Location:1329 → 1441
    MA3; MA3 domain
    pfam02854
    Location:863 → 1091
    MIF4G; MIF4G domain
    pfam03154
    Location:61 → 395
    Atrophin-1; Atrophin-1 family
    cl17013
    Location:1642 → 1688
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  19. XM_030253477.1 → XP_030109337.1  eukaryotic translation initiation factor 4 gamma 3 isoform X17

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (5) summary
    cd11559
    Location:1530 → 1662
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    pfam02847
    Location:1328 → 1440
    MA3; MA3 domain
    pfam02854
    Location:862 → 1090
    MIF4G; MIF4G domain
    pfam03154
    Location:61 → 394
    Atrophin-1; Atrophin-1 family
    cl17013
    Location:1641 → 1687
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  20. XM_030253481.1 → XP_030109341.1  eukaryotic translation initiation factor 4 gamma 3 isoform X19

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1456 → 1588
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:4 → 369
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1254 → 1366
    MA3; MA3 domain
    pfam02854
    Location:788 → 1016
    MIF4G; MIF4G domain
    pfam11235
    Location:202 → 362
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    cl17013
    Location:1567 → 1613
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  21. XM_030253486.1 → XP_030109346.1  eukaryotic translation initiation factor 4 gamma 3 isoform X21

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1429 → 1561
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:2 → 342
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1227 → 1339
    MA3; MA3 domain
    pfam02854
    Location:761 → 989
    MIF4G; MIF4G domain
    pfam11235
    Location:175 → 335
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    cl17013
    Location:1540 → 1586
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  22. XM_036164074.1 → XP_036019967.1  eukaryotic translation initiation factor 4 gamma 3 isoform X22

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1428 → 1560
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:2 → 341
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:172 → 335
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1226 → 1338
    MA3; MA3 domain
    pfam02854
    Location:760 → 988
    MIF4G; MIF4G domain
    cl17013
    Location:1539 → 1585
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  23. XM_036164080.1 → XP_036019973.1  eukaryotic translation initiation factor 4 gamma 3 isoform X30

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (5) summary
    cd11559
    Location:1280 → 1412
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PRK07003
    Location:23 → 187
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1078 → 1190
    MA3; MA3 domain
    pfam02854
    Location:612 → 840
    MIF4G; MIF4G domain
    cl17013
    Location:1391 → 1437
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  24. XM_006538793.4 → XP_006538856.1  eukaryotic translation initiation factor 4 gamma 3 isoform X23

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1425 → 1557
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:6 → 338
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1223 → 1335
    MA3; MA3 domain
    pfam02854
    Location:757 → 985
    MIF4G; MIF4G domain
    pfam11235
    Location:171 → 331
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    cl17013
    Location:1536 → 1582
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  25. XM_006538794.4 → XP_006538857.1  eukaryotic translation initiation factor 4 gamma 3 isoform X24

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    UniProtKB/TrEMBL
    A2AMI2
    Related
    ENSMUSP00000081233.6, ENSMUST00000084215.12
    Conserved Domains (6) summary
    cd11559
    Location:1418 → 1550
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PRK10263
    Location:10 → 315
    PRK10263; DNA translocase FtsK; Provisional
    pfam02847
    Location:1216 → 1328
    MA3; MA3 domain
    pfam02854
    Location:750 → 978
    MIF4G; MIF4G domain
    pfam11235
    Location:164 → 324
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    cl17013
    Location:1529 → 1575
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  26. XM_030253492.1 → XP_030109352.1  eukaryotic translation initiation factor 4 gamma 3 isoform X25

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1417 → 1549
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:5 → 340
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:161 → 324
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1215 → 1327
    MA3; MA3 domain
    pfam02854
    Location:749 → 977
    MIF4G; MIF4G domain
    cl17013
    Location:1528 → 1574
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  27. XM_036164078.1 → XP_036019971.1  eukaryotic translation initiation factor 4 gamma 3 isoform X29

    UniProtKB/TrEMBL
    Z4YKC4
    Conserved Domains (6) summary
    cd11559
    Location:1398 → 1530
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:5 → 340
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:161 → 324
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1196 → 1308
    MA3; MA3 domain
    pfam02854
    Location:749 → 977
    MIF4G; MIF4G domain
    cl17013
    Location:1509 → 1555
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  28. XM_030253498.1 → XP_030109358.1  eukaryotic translation initiation factor 4 gamma 3 isoform X32

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (4) summary
    cd11559
    Location:1169 → 1301
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    pfam02847
    Location:967 → 1079
    MA3; MA3 domain
    pfam02854
    Location:501 → 729
    MIF4G; MIF4G domain
    cl17013
    Location:1280 → 1326
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  29. XM_036164084.1 → XP_036019977.1  eukaryotic translation initiation factor 4 gamma 3 isoform X33

    UniProtKB/TrEMBL
    Z4YKC4
    Conserved Domains (4) summary
    cd11559
    Location:1150 → 1282
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    pfam02847
    Location:948 → 1060
    MA3; MA3 domain
    pfam02854
    Location:501 → 729
    MIF4G; MIF4G domain
    cl17013
    Location:1261 → 1307
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  30. XM_030253496.1 → XP_030109356.1  eukaryotic translation initiation factor 4 gamma 3 isoform X31

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (5) summary
    cd11559
    Location:1279 → 1411
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PRK07003
    Location:23 → 186
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1077 → 1189
    MA3; MA3 domain
    pfam02854
    Location:611 → 839
    MIF4G; MIF4G domain
    cl17013
    Location:1390 → 1436
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  31. XM_030253499.1 → XP_030109359.1  eukaryotic translation initiation factor 4 gamma 3 isoform X32

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (4) summary
    cd11559
    Location:1169 → 1301
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    pfam02847
    Location:967 → 1079
    MA3; MA3 domain
    pfam02854
    Location:501 → 729
    MIF4G; MIF4G domain
    cl17013
    Location:1280 → 1326
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  32. XM_030253487.1 → XP_030109347.1  eukaryotic translation initiation factor 4 gamma 3 isoform X21

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1429 → 1561
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:2 → 342
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1227 → 1339
    MA3; MA3 domain
    pfam02854
    Location:761 → 989
    MIF4G; MIF4G domain
    pfam11235
    Location:175 → 335
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    cl17013
    Location:1540 → 1586
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  33. XM_036164076.1 → XP_036019969.1  eukaryotic translation initiation factor 4 gamma 3 isoform X26

    UniProtKB/TrEMBL
    Z4YKC4
    Conserved Domains (6) summary
    cd11559
    Location:1410 → 1542
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:2 → 342
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:172 → 336
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1208 → 1320
    MA3; MA3 domain
    pfam02854
    Location:761 → 989
    MIF4G; MIF4G domain
    cl17013
    Location:1521 → 1567
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  34. XM_036164075.1 → XP_036019968.1  eukaryotic translation initiation factor 4 gamma 3 isoform X22

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1428 → 1560
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:2 → 341
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:172 → 335
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1226 → 1338
    MA3; MA3 domain
    pfam02854
    Location:760 → 988
    MIF4G; MIF4G domain
    cl17013
    Location:1539 → 1585
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  35. XM_036164081.1 → XP_036019974.1  eukaryotic translation initiation factor 4 gamma 3 isoform X30

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (5) summary
    cd11559
    Location:1280 → 1412
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PRK07003
    Location:23 → 187
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1078 → 1190
    MA3; MA3 domain
    pfam02854
    Location:612 → 840
    MIF4G; MIF4G domain
    cl17013
    Location:1391 → 1437
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  36. XM_030253490.1 → XP_030109350.1  eukaryotic translation initiation factor 4 gamma 3 isoform X24

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    UniProtKB/TrEMBL
    A2AMI2
    Conserved Domains (6) summary
    cd11559
    Location:1418 → 1550
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PRK10263
    Location:10 → 315
    PRK10263; DNA translocase FtsK; Provisional
    pfam02847
    Location:1216 → 1328
    MA3; MA3 domain
    pfam02854
    Location:750 → 978
    MIF4G; MIF4G domain
    pfam11235
    Location:164 → 324
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    cl17013
    Location:1529 → 1575
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  37. XM_030253493.1 → XP_030109353.1  eukaryotic translation initiation factor 4 gamma 3 isoform X25

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1417 → 1549
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:5 → 340
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:161 → 324
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1215 → 1327
    MA3; MA3 domain
    pfam02854
    Location:749 → 977
    MIF4G; MIF4G domain
    cl17013
    Location:1528 → 1574
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  38. XM_006538790.4 → XP_006538853.1  eukaryotic translation initiation factor 4 gamma 3 isoform X19

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1456 → 1588
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:4 → 369
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1254 → 1366
    MA3; MA3 domain
    pfam02854
    Location:788 → 1016
    MIF4G; MIF4G domain
    pfam11235
    Location:202 → 362
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    cl17013
    Location:1567 → 1613
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  39. XM_030253488.1 → XP_030109348.1  eukaryotic translation initiation factor 4 gamma 3 isoform X21

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1429 → 1561
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:2 → 342
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1227 → 1339
    MA3; MA3 domain
    pfam02854
    Location:761 → 989
    MIF4G; MIF4G domain
    pfam11235
    Location:175 → 335
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    cl17013
    Location:1540 → 1586
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  40. XM_030253489.1 → XP_030109349.1  eukaryotic translation initiation factor 4 gamma 3 isoform X22

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1428 → 1560
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:2 → 341
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:172 → 335
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1226 → 1338
    MA3; MA3 domain
    pfam02854
    Location:760 → 988
    MIF4G; MIF4G domain
    cl17013
    Location:1539 → 1585
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  41. XM_030253491.1 → XP_030109351.1  eukaryotic translation initiation factor 4 gamma 3 isoform X24

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    UniProtKB/TrEMBL
    A2AMI2
    Conserved Domains (6) summary
    cd11559
    Location:1418 → 1550
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PRK10263
    Location:10 → 315
    PRK10263; DNA translocase FtsK; Provisional
    pfam02847
    Location:1216 → 1328
    MA3; MA3 domain
    pfam02854
    Location:750 → 978
    MIF4G; MIF4G domain
    pfam11235
    Location:164 → 324
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    cl17013
    Location:1529 → 1575
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  42. XM_036164077.1 → XP_036019970.1  eukaryotic translation initiation factor 4 gamma 3 isoform X28

    UniProtKB/TrEMBL
    Z4YKC4
    Conserved Domains (6) summary
    cd11559
    Location:1399 → 1531
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:5 → 341
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:161 → 325
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1197 → 1309
    MA3; MA3 domain
    pfam02854
    Location:750 → 978
    MIF4G; MIF4G domain
    cl17013
    Location:1510 → 1556
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  43. XM_030253494.2 → XP_030109354.1  eukaryotic translation initiation factor 4 gamma 3 isoform X25

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1417 → 1549
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:5 → 340
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:161 → 324
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1215 → 1327
    MA3; MA3 domain
    pfam02854
    Location:749 → 977
    MIF4G; MIF4G domain
    cl17013
    Location:1528 → 1574
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  44. XM_036164079.1 → XP_036019972.1  eukaryotic translation initiation factor 4 gamma 3 isoform X29

    UniProtKB/TrEMBL
    Z4YKC4
    Conserved Domains (6) summary
    cd11559
    Location:1398 → 1530
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:5 → 340
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:161 → 324
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1196 → 1308
    MA3; MA3 domain
    pfam02854
    Location:749 → 977
    MIF4G; MIF4G domain
    cl17013
    Location:1509 → 1555
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  45. XM_036164082.1 → XP_036019975.1  eukaryotic translation initiation factor 4 gamma 3 isoform X31

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (5) summary
    cd11559
    Location:1279 → 1411
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PRK07003
    Location:23 → 186
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1077 → 1189
    MA3; MA3 domain
    pfam02854
    Location:611 → 839
    MIF4G; MIF4G domain
    cl17013
    Location:1390 → 1436
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  46. XM_030253482.1 → XP_030109342.1  eukaryotic translation initiation factor 4 gamma 3 isoform X19

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1456 → 1588
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:4 → 369
    PHA03247; large tegument protein UL36; Provisional
    pfam02847
    Location:1254 → 1366
    MA3; MA3 domain
    pfam02854
    Location:788 → 1016
    MIF4G; MIF4G domain
    pfam11235
    Location:202 → 362
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    cl17013
    Location:1567 → 1613
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  47. XM_030253484.1 → XP_030109344.1  eukaryotic translation initiation factor 4 gamma 3 isoform X20

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1455 → 1587
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:4 → 368
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:199 → 362
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1253 → 1365
    MA3; MA3 domain
    pfam02854
    Location:787 → 1015
    MIF4G; MIF4G domain
    cl17013
    Location:1566 → 1612
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  48. XM_006538795.4 → XP_006538858.1  eukaryotic translation initiation factor 4 gamma 3 isoform X27

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (6) summary
    cd11559
    Location:1424 → 1556
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PHA03247
    Location:6 → 337
    PHA03247; large tegument protein UL36; Provisional
    PRK07003
    Location:168 → 331
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1222 → 1334
    MA3; MA3 domain
    pfam02854
    Location:756 → 984
    MIF4G; MIF4G domain
    cl17013
    Location:1535 → 1581
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon

  49. XM_030253497.1 → XP_030109357.1  eukaryotic translation initiation factor 4 gamma 3 isoform X31

    UniProtKB/Swiss-Prot
    Q6GQV5, Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0
    Conserved Domains (5) summary
    cd11559
    Location:1279 → 1411
    W2_eIF4G1_like; C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins
    PRK07003
    Location:23 → 186
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam02847
    Location:1077 → 1189
    MA3; MA3 domain
    pfam02854
    Location:611 → 839
    MIF4G; MIF4G domain
    cl17013
    Location:1390 → 1436
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80XI3.2 GenPept UniProtKB/Swiss-Prot:Q80XI3

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