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Zfp362 zinc finger protein 362 [ Mus musculus (house mouse) ]

Gene ID: 230761, updated on 3-Apr-2024

Summary

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Official Symbol
Zfp362provided by MGI
Official Full Name
zinc finger protein 362provided by MGI
Primary source
MGI:MGI:2652839
See related
Ensembl:ENSMUSG00000028799 AllianceGenome:MGI:2652839
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Orthologous to human ZNF362 (zinc finger protein 362). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 27.1), ovary adult (RPKM 26.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
4 D2.2; 4 62.25 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (128666881..128700118, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (128773085..128806112, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene polyhomeotic 2 Neighboring gene STARR-seq mESC enhancer starr_11460 Neighboring gene predicted gene, 33712 Neighboring gene STARR-positive B cell enhancer ABC_E9595 Neighboring gene alpha 1,3-galactosyltransferase 2 Neighboring gene STARR-positive B cell enhancer ABC_E3514 Neighboring gene STARR-seq mESC enhancer starr_11464 Neighboring gene predicted gene, 52679 Neighboring gene STARR-positive B cell enhancer ABC_E6220 Neighboring gene STARR-seq mESC enhancer starr_11466 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 33814

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation.
    Title: Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 362

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081098.2 → NP_001074567.1  zinc finger protein 362 isoform a

    See identical proteins and their annotated locations for NP_001074567.1

    Status: VALIDATED

    Source sequence(s)
    AL611983
    Consensus CDS
    CCDS38884.1
    UniProtKB/TrEMBL
    B1ASA5, E9QA68
    Related
    ENSMUSP00000101686.3, ENSMUST00000106072.9
    Conserved Domains (5) summary
    COG5189
    Location:305 → 357
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    PRK14971
    Location:27 → 131
    PRK14971; DNA polymerase III subunit gamma/tau
    sd00017
    Location:255 → 275
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:253 → 275
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:267 → 292
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001419423.1 → NP_001406352.1  zinc finger protein 362 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL611983
    UniProtKB/TrEMBL
    B1ASA5

  3. NM_001419424.1 → NP_001406353.1  zinc finger protein 362 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL611983
    UniProtKB/TrEMBL
    B1ASA5

  4. NM_001419425.1 → NP_001406354.1  zinc finger protein 362 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL611983
    Related
    ENSMUSP00000128499.2, ENSMUST00000170934.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    128666881..128700118 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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