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Tmem125 transmembrane protein 125 [ Mus musculus (house mouse) ]

Gene ID: 230678, updated on 5-Mar-2024

Summary

Official Symbol
Tmem125provided by MGI
Official Full Name
transmembrane protein 125provided by MGI
Primary source
MGI:MGI:1923409
See related
Ensembl:ENSMUSG00000050854 AllianceGenome:MGI:1923409
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6330530A05Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in brain and heart ventricle. Orthologous to human TMEM125 (transmembrane protein 125). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in stomach adult (RPKM 12.6), duodenum adult (RPKM 12.1) and 17 other tissues See more
Orthologs
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Genomic context

Location:
4 D2.1; 4 54.81 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (118398138..118402110, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (118540941..118544920, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2610528J11 gene Neighboring gene ribosomal protein S5 pseudogene Neighboring gene predicted gene, 40237 Neighboring gene cilia and flagella associated protein 57 Neighboring gene predicted gene, 52677

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC48203

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172383.3NP_759015.2  transmembrane protein 125

    See identical proteins and their annotated locations for NP_759015.2

    Status: VALIDATED

    Source sequence(s)
    AK162907, BB653717, BU700816
    Consensus CDS
    CCDS51285.1
    UniProtKB/Swiss-Prot
    A2BI56, Q8BHY6, Q8CHQ6
    Related
    ENSMUSP00000063157.4, ENSMUST00000060214.10
    Conserved Domains (1) summary
    pfam15109
    Location:15125
    TMEM125; TMEM125 protein family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    118398138..118402110 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017320149.3XP_017175638.1  transmembrane protein 125 isoform X1

    UniProtKB/Swiss-Prot
    A2BI56, Q8BHY6, Q8CHQ6
    Conserved Domains (1) summary
    pfam15109
    Location:15125
    TMEM125; TMEM125 protein family
  2. XM_006503013.5XP_006503076.1  transmembrane protein 125 isoform X1

    See identical proteins and their annotated locations for XP_006503076.1

    UniProtKB/Swiss-Prot
    A2BI56, Q8BHY6, Q8CHQ6
    Conserved Domains (1) summary
    pfam15109
    Location:15125
    TMEM125; TMEM125 protein family
  3. XM_011240496.4XP_011238798.1  transmembrane protein 125 isoform X1

    See identical proteins and their annotated locations for XP_011238798.1

    UniProtKB/Swiss-Prot
    A2BI56, Q8BHY6, Q8CHQ6
    Conserved Domains (1) summary
    pfam15109
    Location:15125
    TMEM125; TMEM125 protein family
  4. XM_006503014.4XP_006503077.1  transmembrane protein 125 isoform X1

    See identical proteins and their annotated locations for XP_006503077.1

    UniProtKB/Swiss-Prot
    A2BI56, Q8BHY6, Q8CHQ6
    Conserved Domains (1) summary
    pfam15109
    Location:15125
    TMEM125; TMEM125 protein family