Zyg11a zyg-11 family member A, cell cycle regulator [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zyg11aprovided by MGI
Official Full Name: zyg-11 family member A, cell cycle regulatorprovided by MGI
Primary source: MGI:MGI:2446208
See related: Ensembl:ENSMUSG00000034645 AllianceGenome:MGI:2446208
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to be part of Cul2-RING ubiquitin ligase complex. Orthologous to human ZYG11A (zyg-11 family member A, cell cycle regulator). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in liver adult (RPKM 1.6), mammary gland adult (RPKM 1.2) and 12 other tissues See more
Orthologs: human all
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Genomic context

Location:: 4 C7; 4 50.31 cM

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	4	NC_000070.7 (108037442..108075285, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	4	NC_000070.6 (108180245..108218088, complement)

Chromosome 4 - NC_000070.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Component	Evidence Code	Pubs
part_of Cul2-RING ubiquitin ligase complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protein zyg-11 homolog A

Names: zyg-11 homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001167936.3 → NP_001161408.2 protein zyg-11 homolog A

Status: VALIDATED

Source sequence(s)

BX293563

Consensus CDS

CCDS51256.2

UniProtKB/TrEMBL

A0A217FL76, F8WHU3

Related

ENSMUSP00000102301.3, ENSMUST00000106690.9

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000070.7 Reference GRCm39 C57BL/6J

Range

108037442..108075285 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006502976.4 → XP_006503039.1 protein zyg-11 homolog A isoform X1

UniProtKB/TrEMBL

A0A1Y7VNL1, F8WHU3

Related

ENSMUSP00000152477.2, ENSMUST00000223127.2

Conserved Domains (2) summary

COG4886
Location:156 → 294

LRR; Leucine-rich repeat (LRR) protein [Transcription]

sd00034
Location:158 → 182

LRR_AMN1; leucine-rich repeat [structural motif]
XM_017320136.1 → XP_017175625.1 protein zyg-11 homolog A isoform X2

UniProtKB/Swiss-Prot

A2BFL2, Q8VC01

Conserved Domains (2) summary

COG4886
Location:56 → 194

LRR; Leucine-rich repeat (LRR) protein [Transcription]

sd00034
Location:58 → 82

LRR_AMN1; leucine-rich repeat [structural motif]