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Ttc22 tetratricopeptide repeat domain 22 [ Mus musculus (house mouse) ]

Gene ID: 230576, updated on 5-Mar-2024

Summary

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Official Symbol
Ttc22provided by MGI
Official Full Name
tetratricopeptide repeat domain 22provided by MGI
Primary source
MGI:MGI:3045307
See related
Ensembl:ENSMUSG00000034919 AllianceGenome:MGI:3045307
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4732467L16Rik
Summary
Is expressed in anal canal; bladder; epidermis; external naris epithelium; and renal calyx. Orthologous to human TTC22 (tetratricopeptide repeat domain 22). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon adult (RPKM 45.3), small intestine adult (RPKM 35.7) and 4 other tissues See more
Orthologs
human all
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Genomic context

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Location:
4 C7; 4 49.67 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (106479646..106497393)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (106622449..106640196)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_10995 Neighboring gene 24-dehydrocholesterol reductase Neighboring gene STARR-seq mESC enhancer starr_10996 Neighboring gene ciliary microtubule associated protein 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:106287642-106287893 Neighboring gene STARR-positive B cell enhancer ABC_E10244 Neighboring gene STARR-positive B cell enhancer ABC_E2700 Neighboring gene prolyl-tRNA synthetase (mitochondrial)(putative) Neighboring gene tetratricopeptide repeat domain 4 Neighboring gene STARR-positive B cell enhancer ABC_E6195

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
tetratricopeptide repeat protein 22
Names
TPR repeat protein 22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177667.5 → NP_808335.1  tetratricopeptide repeat protein 22

    See identical proteins and their annotated locations for NP_808335.1

    Status: VALIDATED

    Source sequence(s)
    AK028895, AL929585
    Consensus CDS
    CCDS18422.1
    UniProtKB/Swiss-Prot
    Q8C159
    UniProtKB/TrEMBL
    A2AVQ6
    Related
    ENSMUSP00000035773.3, ENSMUST00000047922.3
    Conserved Domains (2) summary
    TIGR03903
    Location:410 → 466
    TOMM_kin_cyc; TOMM system kinase/cyclase fusion protein
    sd00006
    Location:65 → 95
    TPR; TPR repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    106479646..106497393
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006502944.3 → XP_006503007.1  tetratricopeptide repeat protein 22 isoform X1

    Conserved Domains (1) summary
    TIGR03903
    Location:223 → 279
    TOMM_kin_cyc; TOMM system kinase/cyclase fusion protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C159.1 GenPept UniProtKB/Swiss-Prot:Q8C159

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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