Tram1l1 translocation associated membrane protein 1-like 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tram1l1provided by MGI
Official Full Name: translocation associated membrane protein 1-like 1provided by MGI
Primary source: MGI:MGI:2443503
See related: Ensembl:ENSMUSG00000044528 AllianceGenome:MGI:2443503
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: A830091N21Rik
Summary: Predicted to be involved in protein insertion into ER membrane. Predicted to act upstream of or within protein transport. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human TRAM1L1 (translocation associated membrane protein 1 like 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human all
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Genomic context

Location:: 3 G1; 3 54.68 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	3	NC_000069.7 (124114686..124116909)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	3	NC_000069.6 (124321037..124323260)

Chromosome 3 - NC_000069.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in SRP-dependent cotranslational protein targeting to membrane, translocation	IEA Inferred from Electronic Annotation more info
involved_in protein insertion into ER membrane	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: translocating chain-associated membrane protein 1-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_146140.4 → NP_666252.1 translocating chain-associated membrane protein 1-like 1

See identical proteins and their annotated locations for NP_666252.1

Status: VALIDATED

Source sequence(s)

AC114625

Consensus CDS

CCDS17819.1

UniProtKB/Swiss-Prot

Q8C455, Q8C6X6, Q8QZR0

Related

ENSMUSP00000062635.5, ENSMUST00000058994.6

Conserved Domains (2) summary

smart00724
Location:116 → 324

TLC; TRAM, LAG1 and CLN8 homology domains

pfam08390
Location:50 → 114

TRAM1; TRAM1-like protein