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Golph3l golgi phosphoprotein 3-like [ Mus musculus (house mouse) ]

Gene ID: 229593, updated on 3-Apr-2024

Summary

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Official Symbol
Golph3lprovided by MGI
Official Full Name
golgi phosphoprotein 3-likeprovided by MGI
Primary source
MGI:MGI:1917129
See related
Ensembl:ENSMUSG00000046519 AllianceGenome:MGI:1917129
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gpp34r; 2010204I15Rik
Summary
Predicted to enable phosphatidylinositol-4-phosphate binding activity. Predicted to be involved in Golgi organization; Golgi vesicle transport; and positive regulation of protein secretion. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi cisterna; cytosol; and trans-Golgi network. Orthologous to human GOLPH3L (golgi phosphoprotein 3 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in colon adult (RPKM 12.9), liver E14 (RPKM 11.0) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
3 F2.1; 3 40.74 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (95496280..95526553)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (95588915..95619247)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene high mobility group box 1, pseudogene 5 Neighboring gene cathepsin S Neighboring gene HORMA domain containing 1 Neighboring gene STARR-positive B cell enhancer mm9_chr3:95392515-95392816 Neighboring gene predicted gene, 40097 Neighboring gene ribosomal protein S10, pseudogene 1 Neighboring gene endosulfine alpha

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC28597

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidylinositol-4-phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol-4-phosphate binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Golgi organization ISO
Inferred from Sequence Orthology
more info
  
involved_in Golgi to plasma membrane protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Golgi vesicle budding IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of protein secretion ISO
Inferred from Sequence Orthology
more info
  
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
is_active_in Golgi cisterna IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Golgi phosphoprotein 3-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177669.2 → NP_001171140.2  Golgi phosphoprotein 3-like isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC092203, AC092479
    Consensus CDS
    CCDS57235.1
    Related
    ENSMUSP00000135406.3, ENSMUST00000177389.8

  2. NM_001177670.2 → NP_001171141.2  Golgi phosphoprotein 3-like isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC092203, AC092479
    Consensus CDS
    CCDS57234.1
    Related
    ENSMUSP00000134804.3, ENSMUST00000176755.8

  3. NM_001404119.1 → NP_001391048.1  Golgi phosphoprotein 3-like isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC092203, AC092479
    UniProtKB/Swiss-Prot
    Q3TIX2, Q3TV24, Q8R088

  4. NM_001404120.1 → NP_001391049.1  Golgi phosphoprotein 3-like isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC092203, AC092479
    UniProtKB/Swiss-Prot
    Q3TIX2, Q3TV24, Q8R088

  5. NM_001404121.1 → NP_001391050.1  Golgi phosphoprotein 3-like isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC092203, AC092479
    UniProtKB/TrEMBL
    H3BJ82
    Related
    ENSMUSP00000134885.3, ENSMUST00000176674.8

  6. NM_001404122.1 → NP_001391051.1  Golgi phosphoprotein 3-like isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC092203, AC092479

  7. NM_001404123.1 → NP_001391052.1  Golgi phosphoprotein 3-like isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC092203, AC092479
    UniProtKB/TrEMBL
    H3BJN5
    Related
    ENSMUSP00000135056.3, ENSMUST00000176541.2

  8. NM_146133.4 → NP_666245.3  Golgi phosphoprotein 3-like isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC092203, AC092479
    Consensus CDS
    CCDS17616.2
    UniProtKB/Swiss-Prot
    Q3TIX2, Q3TV24, Q8R088
    Related
    ENSMUSP00000134799.3, ENSMUST00000177390.8

RNA

  1. NR_175818.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC092203, AC092479

  2. NR_175819.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC092203, AC092479

  3. NR_175821.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC092203, AC092479

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    95496280..95526553
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8R088.1 GenPept UniProtKB/Swiss-Prot:Q8R088

Gene LinkOut

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