U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mettl25b methyltransferase like 25B [ Mus musculus (house mouse) ]

Gene ID: 229503, updated on 5-Mar-2024

Summary

Official Symbol
Mettl25bprovided by MGI
Official Full Name
methyltransferase like 25Bprovided by MGI
Primary source
MGI:MGI:2387197
See related
Ensembl:ENSMUSG00000004896 AllianceGenome:MGI:2387197
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rrnad1
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human METTL25B (methyltransferase like 25B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 11.5), CNS E14 (RPKM 10.8) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Mettl25b in Genome Data Viewer
Location:
3 F1; 3 38.78 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (87829908..87838337, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (87922601..87930719, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene papillary renal cell carcinoma (translocation-associated) Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:87689595-87689778 Neighboring gene STARR-seq mESC enhancer starr_08164 Neighboring gene STARR-seq mESC enhancer starr_08165 Neighboring gene heparin binding growth factor Neighboring gene STARR-positive B cell enhancer ABC_E10190 Neighboring gene mitochondrial ribosomal protein L24 Neighboring gene STARR-positive B cell enhancer ABC_E9556 Neighboring gene interferon stimulated exonuclease gene 20-like 2 Neighboring gene cellular retinoic acid binding protein II Neighboring gene STARR-positive B cell enhancer ABC_E9216 Neighboring gene predicted gene, 32518

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

Markers

Clone Names

  • MGC38548

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
methyltransferase-like protein 25B
Names
protein RRNAD1
ribosomal RNA adenine dimethylase domain containing 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153562.4NP_705790.3  methyltransferase-like protein 25B

    See identical proteins and their annotated locations for NP_705790.3

    Status: VALIDATED

    Source sequence(s)
    AA611348, AI592533, AK035389, BB684061, BB871494, BY035934, BY617418
    Consensus CDS
    CCDS17458.1
    UniProtKB/Swiss-Prot
    G3X8Q8, Q8BZG5, Q8CII4
    Related
    ENSMUSP00000005016.10, ENSMUST00000005016.16
    Conserved Domains (1) summary
    pfam13679
    Location:133293
    Methyltransf_32; Methyltransferase domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    87829908..87838337 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501338.5XP_006501401.1  methyltransferase-like protein 25B isoform X1

    Conserved Domains (1) summary
    pfam13679
    Location:124284
    Methyltransf_32; Methyltransferase domain
  2. XM_030252571.2XP_030108431.1  methyltransferase-like protein 25B isoform X5

    Conserved Domains (1) summary
    pfam13679
    Location:63223
    Methyltransf_32; Methyltransferase domain
  3. XM_036163045.1XP_036018938.1  methyltransferase-like protein 25B isoform X3

    Conserved Domains (1) summary
    cl17173
    Location:133272
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  4. XM_006501340.4XP_006501403.1  methyltransferase-like protein 25B isoform X4

    UniProtKB/TrEMBL
    E9PUL0
    Related
    ENSMUSP00000125365.2, ENSMUST00000160074.8
    Conserved Domains (1) summary
    pfam13679
    Location:69229
    Methyltransf_32; Methyltransferase domain
  5. XM_030252572.1XP_030108432.1  methyltransferase-like protein 25B isoform X6

    Conserved Domains (1) summary
    cl17173
    Location:2123
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  6. XM_030252570.2XP_030108430.1  methyltransferase-like protein 25B isoform X2

    Conserved Domains (1) summary
    cl17173
    Location:124263
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  7. XM_036163047.1XP_036018940.1  methyltransferase-like protein 25B isoform X7

RNA

  1. XR_003954313.2 RNA Sequence

  2. XR_375513.5 RNA Sequence

  3. XR_003954311.1 RNA Sequence

  4. XR_375514.5 RNA Sequence

  5. XR_003954312.1 RNA Sequence

  6. XR_003954310.1 RNA Sequence

  7. XR_375515.5 RNA Sequence

  8. XR_003954308.2 RNA Sequence