U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zim1 zinc finger, imprinted 1 [ Mus musculus (house mouse) ]

Gene ID: 22776, updated on 8-Feb-2024

Summary

Go to the top of the page Help
Official Symbol
Zim1provided by MGI
Official Full Name
zinc finger, imprinted 1provided by MGI
Primary source
MGI:MGI:1341879
See related
Ensembl:ENSMUSG00000002266 AllianceGenome:MGI:1341879
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including brain; extraembryonic component; genitourinary system; limb; and ventral grey horn. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in limb E14.5 (RPKM 16.9), placenta adult (RPKM 4.9) and 8 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
7 A1; 7 3.87 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (6677443..6699521, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (6674444..6696540, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_17982 Neighboring gene olfactory receptor family 5 subfamily BW member 2 Neighboring gene zinc finger, imprinted 2 Neighboring gene STARR-seq mESC enhancer starr_17985 Neighboring gene Peg3 opposite strand Neighboring gene paternally expressed 3 Neighboring gene Tctex1 domain containing 2 pseudogene Neighboring gene ubiquitin specific peptidase 29

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Trans-allelic mutational effects at the Peg3 imprinted locus. Bretz CL, et al. PLoS One, 2018. PMID 30335829, Free PMC Article
  2. Zim1, a maternally expressed mouse Kruppel-type zinc-finger gene located in proximal chromosome 7. Kim J, et al. Hum Mol Genet, 1999 May. PMID 10196374
  3. A Novel Mutant Allele of Pw1/Peg3 Does Not Affect Maternal Behavior or Nursing Behavior. Denizot AL, et al. PLoS Genet, 2016 May. PMID 27187722, Free PMC Article
  4. Analysis of imprinted murine Peg3 locus in transgenic mice. Szeto IY, et al. Mamm Genome, 2004 Apr. PMID 15112106
  5. Discovery of a novel, paternally expressed ubiquitin-specific processing protease gene through comparative analysis of an imprinted region of mouse chromosome 7 and human chromosome 19q13.4. Kim J, et al. Genome Res, 2000 Aug. PMID 10958632, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Chemically induced (ENU) (3)  1 citation
  • Endonuclease-mediated (3) 

General gene information

Go to the top of the page Help

Markers

Homology

General protein information

Go to the top of the page Help
Preferred Names
zinc finger, imprinted 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011769.4 → NP_035899.4  zinc finger, imprinted 1

    See identical proteins and their annotated locations for NP_035899.4

    Status: VALIDATED

    Source sequence(s)
    AK086590, BC066196, CD349354
    Consensus CDS
    CCDS20782.1
    UniProtKB/TrEMBL
    Q8C393
    Related
    ENSMUSP00000002336.9, ENSMUST00000002336.16
    Conserved Domains (5) summary
    PRK13335
    Location:137 → 269
    PRK13335; superantigen-like protein SSL3; Reviewed
    smart00349
    Location:50 → 105
    KRAB; krueppel associated box
    COG5048
    Location:226 → 427
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:327 → 347
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:437 → 459
    zf-C2H2; Zinc finger, C2H2 type

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    6677443..6699521 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011250495.3 → XP_011248797.1  zinc finger, imprinted 1 isoform X1

    See identical proteins and their annotated locations for XP_011248797.1

    UniProtKB/TrEMBL
    Q8C393
    Conserved Domains (5) summary
    PRK13335
    Location:137 → 269
    PRK13335; superantigen-like protein SSL3; Reviewed
    smart00349
    Location:50 → 105
    KRAB; krueppel associated box
    COG5048
    Location:226 → 427
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:327 → 347
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:437 → 459
    zf-C2H2; Zinc finger, C2H2 type

  2. XM_011250499.3 → XP_011248801.1  zinc finger, imprinted 1 isoform X1

    See identical proteins and their annotated locations for XP_011248801.1

    UniProtKB/TrEMBL
    Q8C393
    Conserved Domains (5) summary
    PRK13335
    Location:137 → 269
    PRK13335; superantigen-like protein SSL3; Reviewed
    smart00349
    Location:50 → 105
    KRAB; krueppel associated box
    COG5048
    Location:226 → 427
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:327 → 347
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:437 → 459
    zf-C2H2; Zinc finger, C2H2 type

  3. XM_011250498.3 → XP_011248800.1  zinc finger, imprinted 1 isoform X2

    Conserved Domains (4) summary
    PRK13335
    Location:59 → 191
    PRK13335; superantigen-like protein SSL3; Reviewed
    COG5048
    Location:148 → 349
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:249 → 269
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:1 → 27
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

  4. XM_011250497.3 → XP_011248799.1  zinc finger, imprinted 1 isoform X1

    See identical proteins and their annotated locations for XP_011248799.1

    UniProtKB/TrEMBL
    Q8C393
    Conserved Domains (5) summary
    PRK13335
    Location:137 → 269
    PRK13335; superantigen-like protein SSL3; Reviewed
    smart00349
    Location:50 → 105
    KRAB; krueppel associated box
    COG5048
    Location:226 → 427
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:327 → 347
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:437 → 459
    zf-C2H2; Zinc finger, C2H2 type
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous