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Zfp93 zinc finger protein 93 [ Mus musculus (house mouse) ]

Gene ID: 22755, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp93provided by MGI
Official Full Name
zinc finger protein 93provided by MGI
Primary source
MGI:MGI:107611
See related
Ensembl:ENSMUSG00000055305 AllianceGenome:MGI:107611
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf235
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in bladder; female associated reproductive structure; and ureter. Orthologous to human ZNF235 (zinc finger protein 235). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 1.4), CNS E14 (RPKM 1.3) and 28 other tissues See more
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Genomic context

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Location:
7 A3; 7 10.27 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (23967406..23977219)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (24267984..24277794)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 109 Neighboring gene zinc finger protein 108 Neighboring gene STARR-seq mESC enhancer starr_18256 Neighboring gene predicted gene, 51471 Neighboring gene zinc finger protein 51 pseudogene Neighboring gene predicted gene, 50477

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Analysis of homologous XRCC1-linked zinc-finger gene families in human and mouse: evidence for orthologous genes. Shannon M, et al. Genomics, 1998 Apr 1. PMID 9570955
  2. Comparative analysis of a conserved zinc finger gene cluster on human chromosome 19q and mouse chromosome 7. Shannon M, et al. Genomics, 1996 Apr 1. PMID 8617494
  3. Identification of novel ARF binding proteins by two-hybrid screening. Tompkins V, et al. Cell Cycle, 2006 Mar. PMID 16582619
  4. Detailed comparative map of human chromosome 19q and related regions of the mouse genome. Stubbs L, et al. Genomics, 1996 Aug 1. PMID 8812484
  5. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Wiese CB, et al. Front Neurosci, 2012. PMID 22988430, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Zfp93 zinc finger protein 93
    Title: Comparative analysis of a conserved zinc finger gene cluster on human chromosome 19q and mouse chromosome 7.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 235
Names
zfp-93

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360227.1 → NP_001347156.1  zinc finger protein 235 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC159140
    Conserved Domains (3) summary
    COG5048
    Location:275 → 613
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:333 → 353
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:25 → 66
    KRAB; KRAB box

  2. NM_009567.4 → NP_033593.1  zinc finger protein 235 isoform 2

    See identical proteins and their annotated locations for NP_033593.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AK132229
    Consensus CDS
    CCDS39828.1
    UniProtKB/Swiss-Prot
    Q3UKA3, Q61116, Q8CE70
    Related
    ENSMUSP00000104077.4, ENSMUST00000108438.10
    Conserved Domains (4) summary
    COG5048
    Location:257 → 595
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:315 → 335
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:7 → 48
    KRAB; KRAB box
    pfam13465
    Location:608 → 632
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. NR_153420.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 3' end compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AC159140, BM935074

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    23967406..23977219
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017322143.2 → XP_017177632.1  zinc finger protein 235 isoform X1

    UniProtKB/Swiss-Prot
    Q3UKA3, Q61116, Q8CE70
    Conserved Domains (4) summary
    COG5048
    Location:257 → 595
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:315 → 335
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:7 → 48
    KRAB; KRAB box
    pfam13465
    Location:608 → 632
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q61116.1 GenPept UniProtKB/Swiss-Prot:Q61116

Gene LinkOut

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