U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ifi207 interferon activated gene 207 [ Mus musculus (house mouse) ]

Gene ID: 226691, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Ifi207provided by MGI
Official Full Name
interferon activated gene 207provided by MGI
Primary source
MGI:MGI:2138302
See related
Ensembl:ENSMUSG00000073490 AllianceGenome:MGI:2138302
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
pyhinA; Pyhin-A
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in several processes, including regulation of cysteine-type endopeptidase activity; regulation of gene expression; and regulation of innate immune response. Predicted to be located in nucleolus and nucleoplasm. Predicted to colocalize with cytosol. Orthologous to human IFI16 (interferon gamma inducible protein 16). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in mammary gland adult (RPKM 13.2), subcutaneous fat pad adult (RPKM 6.7) and 17 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Ifi207 in Genome Data Viewer
Location:
1 H3; 1 80.61 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (173550993..173569394, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (173723424..173741831, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene pyrin and HIN domain family, member 1 pseudogene Neighboring gene predicted gene 7871 Neighboring gene interferon activated gene 204 Neighboring gene interferon activated gene 203, pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr1:175731887-175732188

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC183622

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables double-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
enables transcription factor binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in activation of innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to interferon-beta IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
colocalizes_with cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein LOC226691
Names
interferon-activatable protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204910.1 → NP_001191839.1  uncharacterized protein LOC226691

    Status: VALIDATED

    Source sequence(s)
    AC117682, AK054438, BE335648, BE634329, BX527645, CJ056316, CJ065456
    Consensus CDS
    CCDS56659.1
    UniProtKB/TrEMBL
    D3Z2E7, E9Q3L4
    Related
    ENSMUSP00000048129.8, ENSMUST00000042610.15
    Conserved Domains (3) summary
    cd08305
    Location:10 → 83
    Pyrin; Pyrin: a protein-protein interaction domain
    pfam02760
    Location:788 → 954
    HIN; HIN-200/IF120x domain
    pfam06752
    Location:608 → 724
    E_Pc_C; Enhancer of Polycomb C-terminus

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    173550993..173569394 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011238800.4 → XP_011237102.1  uncharacterized protein LOC226691 isoform X6

    UniProtKB/TrEMBL
    D3Z2E7
    Conserved Domains (3) summary
    cd08305
    Location:10 → 83
    Pyrin; a protein-protein interaction domain
    pfam05109
    Location:574 → 766
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam02760
    Location:785 → 951
    HIN; HIN-200/IF120x domain

  2. XM_011238799.4 → XP_011237101.1  uncharacterized protein LOC226691 isoform X5

    UniProtKB/TrEMBL
    D3Z2E7
    Conserved Domains (3) summary
    cd08305
    Location:10 → 83
    Pyrin; a protein-protein interaction domain
    pfam05109
    Location:574 → 813
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam02760
    Location:799 → 965
    HIN; HIN-200/IF120x domain

  3. XM_036164142.1 → XP_036020035.1  uncharacterized protein LOC226691 isoform X4

    UniProtKB/TrEMBL
    D3Z2E7
    Conserved Domains (3) summary
    cd08305
    Location:10 → 83
    Pyrin; a protein-protein interaction domain
    pfam05109
    Location:574 → 827
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam02760
    Location:813 → 979
    HIN; HIN-200/IF120x domain

  4. XM_011238798.4 → XP_011237100.1  uncharacterized protein LOC226691 isoform X2

    UniProtKB/TrEMBL
    D3Z2E7
    Conserved Domains (3) summary
    cd08305
    Location:10 → 83
    Pyrin; a protein-protein interaction domain
    pfam05109
    Location:572 → 853
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam02760
    Location:839 → 1005
    HIN; HIN-200/IF120x domain

  5. XM_006496794.5 → XP_006496857.1  uncharacterized protein LOC226691 isoform X3

    UniProtKB/TrEMBL
    D3Z2E7
    Conserved Domains (3) summary
    cd08305
    Location:10 → 83
    Pyrin; a protein-protein interaction domain
    pfam05109
    Location:561 → 842
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam02760
    Location:828 → 994
    HIN; HIN-200/IF120x domain

  6. XM_011238797.4 → XP_011237099.1  uncharacterized protein LOC226691 isoform X1

    UniProtKB/TrEMBL
    D3Z2E7
    Conserved Domains (3) summary
    cd08305
    Location:10 → 83
    Pyrin; a protein-protein interaction domain
    pfam05109
    Location:574 → 855
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam02760
    Location:841 → 1007
    HIN; HIN-200/IF120x domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous