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Zfa-ps zinc finger protein, autosomal, pseudogene [ Mus musculus (house mouse) ]

Gene ID: 22639, updated on 11-Apr-2024

Summary

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Official Symbol
Zfa-psprovided by MGI
Official Full Name
zinc finger protein, autosomal, pseudogeneprovided by MGI
Primary source
MGI:MGI:99153
See related
Ensembl:ENSMUSG00000121690 AllianceGenome:MGI:99153
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zfa; Zfx
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in testis. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
10 B3; 10 26.71 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (52418416..52421835, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (52542320..52545739, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2933 Neighboring gene NUS1 dehydrodolichyl diphosphate synthase subunit Neighboring gene STARR-seq mESC enhancer starr_26679 Neighboring gene STARR-seq mESC enhancer starr_26680 Neighboring gene STARR-seq mESC enhancer starr_26681 Neighboring gene predicted gene, 47612 Neighboring gene predicted gene, 36065 Neighboring gene STARR-seq mESC enhancer starr_26682 Neighboring gene solute carrier family 35, member F1 Neighboring gene VISTA enhancer mm782 Neighboring gene STARR-seq mESC enhancer starr_26684 Neighboring gene predicted gene, 36123

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Retroposon compensatory mechanism hypothesis not supported: Zfa knockout mice are fertile. Banks KG, et al. Genomics, 2003 Sep. PMID 12906850
  2. The musculus-type Y chromosome of the laboratory mouse is of Asian origin. Nagamine CM, et al. Mamm Genome, 1992. PMID 1352158
  3. Gene expression, X-inactivation, and methylation during spermatogenesis: the case of Zfa, Zfx, and Zfy in mice. Erickson RP, et al. Mol Reprod Dev, 1993 Jun. PMID 8318216
  4. Unexpected embryonic stem (ES) cell mutations represent a concern in gene targeting: lessons from "fierce" mice. Kumar RA, et al. Genesis, 2004 Feb. PMID 14994267
  5. Differential rates of evolution for the ZFY-related zinc finger genes, Zfy, Zfx, and Zfa in the mouse genus Mus. Tucker PK, et al. Mol Biol Evol, 2003 Jun. PMID 12716983

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Other Names

  • zinc finger protein X-linked pseudogene
  • zinc finger protein ZFX

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of chromatin ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_037920.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC153948
    Related
    ENSMUST00000180673.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    52418416..52421835 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_009540.3: Suppressed sequence

    Description
    NM_009540.3: This RefSeq was permanently suppressed because it is now thought that this gene is a transcribed pseudogene.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P23607.1 GenPept UniProtKB/Swiss-Prot:P23607

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.