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Prelid3a PRELI domain containing 3A [ Mus musculus (house mouse) ]

Gene ID: 225655, updated on 11-Apr-2024

Summary

Official Symbol
Prelid3aprovided by MGI
Official Full Name
PRELI domain containing 3Aprovided by MGI
Primary source
MGI:MGI:2442865
See related
Ensembl:ENSMUSG00000024530 AllianceGenome:MGI:2442865
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Slmo1; A230074A19Rik
Summary
Predicted to enable phosphatidic acid transfer activity. Predicted to be involved in phospholipid transport. Predicted to act upstream of or within lipid transport. Located in mitochondrion. Orthologous to human PRELID3A (PRELI domain containing 3A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cortex adult (RPKM 7.1), frontal lobe adult (RPKM 7.1) and 10 other tissues See more
Orthologs
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Genomic context

Location:
18 E1; 18 39.99 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (67595119..67613651)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (67462049..67480581)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene tubulin, beta 6 class V Neighboring gene AFG3-like AAA ATPase 2 Neighboring gene STARR-positive B cell enhancer ABC_E3234 Neighboring gene spire type actin nucleation factor 1 Neighboring gene STARR-seq mESC enhancer starr_44904 Neighboring gene STARR-seq mESC enhancer starr_44905 Neighboring gene STARR-seq mESC enhancer starr_44907 Neighboring gene predicted gene, 17669 Neighboring gene STARR-positive B cell enhancer mm9_chr18:67771962-67772263 Neighboring gene centrosomal protein 76

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Clone Names

  • MGC28728

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables phosphatidic acid transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables phosphatidic acid transfer activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within lipid transport IEA
Inferred from Electronic Annotation
more info
 
involved_in phospholipid transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in phospholipid transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in mitochondrial intermembrane space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion HDA PubMed 

General protein information

Preferred Names
PRELI domain containing protein 3A
Names
protein slowmo homolog 1
slowmo homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144867.2NP_659116.1  PRELI domain containing protein 3A

    See identical proteins and their annotated locations for NP_659116.1

    Status: VALIDATED

    Source sequence(s)
    AC154125, AK143220, BY741062
    Consensus CDS
    CCDS37848.1
    UniProtKB/Swiss-Prot
    Q8VE85
    Related
    ENSMUSP00000025411.8, ENSMUST00000025411.9
    Conserved Domains (1) summary
    pfam04707
    Location:15170
    PRELI; PRELI-like family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    67595119..67613651
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006525896.4XP_006525959.1  PRELI domain containing protein 3A isoform X2

    Conserved Domains (1) summary
    pfam04707
    Location:15156
    PRELI; PRELI-like family
  2. XM_006525897.5XP_006525960.1  PRELI domain containing protein 3A isoform X3

    See identical proteins and their annotated locations for XP_006525960.1

    UniProtKB/Swiss-Prot
    Q8VE85
    Conserved Domains (1) summary
    pfam04707
    Location:15170
    PRELI; PRELI-like family
  3. XM_006525895.5XP_006525958.1  PRELI domain containing protein 3A isoform X1

    UniProtKB/TrEMBL
    A0A494B9F8
    Related
    ENSMUSP00000157593.2, ENSMUST00000235414.2
    Conserved Domains (1) summary
    pfam04707
    Location:15155
    PRELI; PRELI-like family

RNA

  1. XR_385989.4 RNA Sequence

  2. XR_001782357.3 RNA Sequence

  3. XR_001782358.3 RNA Sequence