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Lrrc73 leucine rich repeat containing 73 [ Mus musculus (house mouse) ]

Gene ID: 224813, updated on 5-Mar-2024

Summary

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Official Symbol
Lrrc73provided by MGI
Official Full Name
leucine rich repeat containing 73provided by MGI
Primary source
MGI:MGI:2684934
See related
Ensembl:ENSMUSG00000071073 AllianceGenome:MGI:2684934
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm88
Summary
Orthologous to human LRRC73 (leucine rich repeat containing 73). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 45.2), CNS E18 (RPKM 16.7) and 8 other tissues See more
Orthologs
human all
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Genomic context

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Location:
17 C; 17 22.9 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (46564896..46568242)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (46254165..46257316)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E11645 Neighboring gene polymerase (RNA) I polypeptide C Neighboring gene Yip1 domain family, member 3 Neighboring gene tight junction associated protein 1 Neighboring gene predicted gene, 41588 Neighboring gene delta like non-canonical Notch ligand 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
leucine-rich repeat-containing protein 73

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001111142.2 → NP_001104612.1  leucine-rich repeat-containing protein 73 isoform 1

    See identical proteins and their annotated locations for NP_001104612.1

    Status: VALIDATED

    Source sequence(s)
    AC116739
    Consensus CDS
    CCDS50123.1
    UniProtKB/TrEMBL
    B2RWC4
    Related
    ENSMUSP00000156533.2, ENSMUST00000233692.2
    Conserved Domains (2) summary
    cd00116
    Location:5 → 255
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:58 → 86
    LRR_RI; leucine-rich repeat [structural motif]

  2. NM_001417726.1 → NP_001404655.1  leucine-rich repeat-containing protein 73 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC116739
    UniProtKB/TrEMBL
    F6U1P7
    Related
    ENSMUSP00000092896.6, ENSMUST00000095262.6

  3. NM_001417727.1 → NP_001404656.1  leucine-rich repeat-containing protein 73 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC116739

  4. NM_001417728.1 → NP_001404657.1  leucine-rich repeat-containing protein 73 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC116739

RNA

  1. NR_184566.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC116739

  2. NR_184567.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC116739

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    46564896..46568242
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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