U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp472 zinc finger protein 472 [ Mus musculus (house mouse) ]

Gene ID: 224691, updated on 8-Feb-2024

Summary

Go to the top of the page Help
Official Symbol
Zfp472provided by MGI
Official Full Name
zinc finger protein 472provided by MGI
Primary source
MGI:MGI:2385049
See related
Ensembl:ENSMUSG00000053600 AllianceGenome:MGI:2385049
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Krim1; KRIM-1; Krim-1A; Krim-1B
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in early conceptus and genitourinary system. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 2.4), bladder adult (RPKM 2.2) and 23 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
17 B1; 17 17.98 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (33184805..33198185)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (32965831..32979211)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 13 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33084248-33084483 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 41 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E7516 Neighboring gene zinc finger protein 952 Neighboring gene zinc finger protein 763 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33170086-33170195 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33170311-33170494

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional analysis of a novel KRAB/C2H2 zinc finger protein Mipu1. Jiang L, et al. Biochem Biophys Res Commun, 2007 May 18. PMID 17397802
  2. Identification of a novel Krüppel-associated box domain protein, Krim-1, that interacts with c-Myc and inhibits its oncogenic activity. Hennemann H, et al. J Biol Chem, 2003 Aug 1. PMID 12748187
  3. A functional screen to identify novel effectors of hematopoietic stem cell activity. Deneault E, et al. Cell, 2009 Apr 17. PMID 19379700, Free PMC Article
  4. Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR. Agata Y, et al. Gene, 1998 Jun 15. PMID 9630514
  5. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger protein 472
Names
KRAB box containing zinc finger protein
Krab box proteins interacting with myc 1
zin finger protein 472

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153063.3 → NP_694703.2  zinc finger protein 472

    Status: VALIDATED

    Source sequence(s)
    AK142395, BB652931, BQ885210
    Consensus CDS
    CCDS50062.1
    UniProtKB/TrEMBL
    B0V2W5
    Related
    ENSMUSP00000036514.8, ENSMUST00000039132.9
    Conserved Domains (5) summary
    smart00349
    Location:10 → 50
    KRAB; krueppel associated box
    COG5048
    Location:195 → 492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:395 → 415
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:10 → 49
    KRAB; KRAB box
    pfam13465
    Location:435 → 460
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    33184805..33198185
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous