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Cpped1 calcineurin-like phosphoesterase domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 223978, updated on 5-Mar-2024

Summary

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Official Symbol
Cpped1provided by MGI
Official Full Name
calcineurin-like phosphoesterase domain containing 1provided by MGI
Primary source
MGI:MGI:2443300
See related
Ensembl:ENSMUSG00000065979 AllianceGenome:MGI:2443300
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C530044N13Rik
Summary
Predicted to enable metal ion binding activity; protein serine phosphatase activity; and protein threonine phosphatase activity. Predicted to be located in cytosol and plasma membrane. Orthologous to human CPPED1 (calcineurin like phosphoesterase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in kidney adult (RPKM 6.8), large intestine adult (RPKM 6.3) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
16 A1; 16 6.61 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (11621546..11727377, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (11803684..11909476, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene sorting nexin 29 Neighboring gene predicted gene, 32100 Neighboring gene STARR-seq mESC enhancer starr_40110 Neighboring gene RIKEN cDNA 4833415N18 gene Neighboring gene STARR-seq mESC enhancer starr_40111 Neighboring gene STARR-seq mESC enhancer starr_40112 Neighboring gene predicted gene 9961 Neighboring gene predicted gene, 32278 Neighboring gene shisa family member 9 Neighboring gene STARR-seq mESC enhancer starr_40114 Neighboring gene predicted gene, 19571

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  2. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC27760

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables myosin phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
serine/threonine-protein phosphatase CPPED1
Names
Vcalcineurin-like phosphoesterase domain containing 1
calcineurin-like phosphoesterase domain-containing protein 1
NP_001404625.1
NP_001404626.1
NP_001404651.1
NP_001404652.1
NP_001404653.1
NP_666179.2
XP_006522078.1
XP_006522079.1
XP_036015773.1
XP_036015774.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001417696.1 → NP_001404625.1  serine/threonine-protein phosphatase CPPED1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC154508, AC154509

  2. NM_001417697.1 → NP_001404626.1  serine/threonine-protein phosphatase CPPED1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC154508, AC154509
    Related
    ENSMUSP00000112587.2, ENSMUST00000121750.2

  3. NM_001417722.1 → NP_001404651.1  serine/threonine-protein phosphatase CPPED1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC154508, AC154509

  4. NM_001417723.1 → NP_001404652.1  serine/threonine-protein phosphatase CPPED1 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC154508, AC154509

  5. NM_001417724.1 → NP_001404653.1  serine/threonine-protein phosphatase CPPED1 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC154508, AC154509

  6. NM_146067.4 → NP_666179.2  serine/threonine-protein phosphatase CPPED1 isoform 1

    See identical proteins and their annotated locations for NP_666179.2

    Status: VALIDATED

    Source sequence(s)
    AC154508, AC154509
    Consensus CDS
    CCDS27964.1
    UniProtKB/Swiss-Prot
    Q3UYF7, Q8BFS6, Q8BJQ3, Q8BYB7, Q8K236, Q8R3G2
    Related
    ENSMUSP00000093992.5, ENSMUST00000096272.11
    Conserved Domains (2) summary
    COG1409
    Location:33 → 268
    CpdA; 3',5'-cyclic AMP phosphodiesterase CpdA [Signal transduction mechanisms]
    cd07395
    Location:29 → 294
    MPP_CSTP1; Homo sapiens CSTP1 and related proteins, metallophosphatase domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    11621546..11727377 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159880.1 → XP_036015773.1  serine/threonine-protein phosphatase CPPED1 isoform X2

    Conserved Domains (1) summary
    cl13995
    Location:2 → 172
    MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain

  2. XM_006522016.4 → XP_006522079.1  serine/threonine-protein phosphatase CPPED1 isoform X3

    See identical proteins and their annotated locations for XP_006522079.1

    Conserved Domains (1) summary
    cl13995
    Location:53 → 120
    MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain

  3. XM_006522015.4 → XP_006522078.1  serine/threonine-protein phosphatase CPPED1 isoform X3

    See identical proteins and their annotated locations for XP_006522078.1

    Conserved Domains (1) summary
    cl13995
    Location:53 → 120
    MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain

  4. XM_036159881.1 → XP_036015774.1  serine/threonine-protein phosphatase CPPED1 isoform X3

    Related
    ENSMUSP00000089104.6, ENSMUST00000073371.7
    Conserved Domains (1) summary
    cl13995
    Location:53 → 120
    MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BFS6.1 GenPept UniProtKB/Swiss-Prot:Q8BFS6

Gene LinkOut

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