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Spryd3 SPRY domain containing 3 [ Mus musculus (house mouse) ]

Gene ID: 223918, updated on 5-Mar-2024

Summary

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Official Symbol
Spryd3provided by MGI
Official Full Name
SPRY domain containing 3provided by MGI
Primary source
MGI:MGI:2446175
See related
Ensembl:ENSMUSG00000036966 AllianceGenome:MGI:2446175
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be involved in cell surface receptor signaling pathway and cytoskeleton organization. Predicted to be active in cytoplasm. Orthologous to human SPRYD3 (SPRY domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cerebellum adult (RPKM 39.1), cortex adult (RPKM 35.4) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
15 F2; 15 57.3 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (102024961..102044678, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (102116526..102136218, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_39815 Neighboring gene eukaryotic translation initiation factor 4B Neighboring gene predicted gene, 53915 Neighboring gene tensin 2 Neighboring gene STARR-positive B cell enhancer ABC_E482 Neighboring gene insulin-like growth factor binding protein 6 Neighboring gene sterol O-acyltransferase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Markers

Homology

General protein information

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Preferred Names
SPRY domain-containing protein 3
NP_001028449.2
XP_006520949.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033277.3 → NP_001028449.2  SPRY domain-containing protein 3

    See identical proteins and their annotated locations for NP_001028449.2

    Status: VALIDATED

    Source sequence(s)
    AI427285, BG293312, BQ031507, BU057890, BY739425, CA323202, CX201967
    Consensus CDS
    CCDS49738.1
    UniProtKB/TrEMBL
    E9Q9B3, Q3UIZ3
    Related
    ENSMUSP00000121493.2, ENSMUST00000154032.2
    Conserved Domains (1) summary
    cd12908
    Location:220 → 438
    SPRYD3; SPRY domain-containing protein 3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    102024961..102044678 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006520886.4 → XP_006520949.1  SPRY domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    Q3UIZ3
    Conserved Domains (1) summary
    cd12908
    Location:220 → 438
    SPRYD3; SPRY domain-containing protein 3
Nucleotide Protein Strain
Heading Accession and Version

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