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Ugt3a2 UDP glycosyltransferases 3 family, polypeptide A2 [ Mus musculus (house mouse) ]

Gene ID: 223337, updated on 11-Apr-2024

Summary

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Official Symbol
Ugt3a2provided by MGI
Official Full Name
UDP glycosyltransferases 3 family, polypeptide A2provided by MGI
Primary source
MGI:MGI:2145969
See related
Ensembl:ENSMUSG00000049152 AllianceGenome:MGI:2145969
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Enables UDP-glycosyltransferase activity. Predicted to act upstream of or within cellular response to genistein. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to several human genes including UGT3A2 (UDP glycosyltransferase family 3 member A2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 195.0) and liver adult (RPKM 97.2) See more
Orthologs
human all
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Genomic context

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See Ugt3a2 in Genome Data Viewer
Location:
15; 15 A1
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (9335670..9370960)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (9335551..9370955)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene UDP glycosyltransferases 3 family, polypeptide A1 Neighboring gene UDP glycosyltransferases 3 family, polypeptide A1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_37936 Neighboring gene STARR-seq mESC enhancer starr_37937 Neighboring gene UDP glycosyltransferases 3 family, polypeptide A1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_37938 Neighboring gene STARR-seq mESC enhancer starr_37939 Neighboring gene calcyphosine-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymes. Meech R, et al. J Biol Chem, 2012 Jul 13. PMID 22621930, Free PMC Article
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC37820

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables UDP-glycosyltransferase activity ISO
Inferred from Sequence Orthology
more info
 PubMed 
enables glucuronosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to genistein ISO
Inferred from Sequence Orthology
more info
 PubMed 
Component Evidence Code Pubs
part_of UDP-N-acetylglucosamine transferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
UDP-glucuronosyltransferase 3A2
Names
UDP glucuronosyltransferase 3 family, polypeptide A2
UDPGT 3A2
NP_001403339.1
NP_001403340.1
NP_659094.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001416410.1 → NP_001403339.1  UDP-glucuronosyltransferase 3A2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC132893

  2. NM_001416411.1 → NP_001403340.1  UDP-glucuronosyltransferase 3A2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC132893

  3. NM_144845.4 → NP_659094.1  UDP-glucuronosyltransferase 3A2 isoform 1 precursor

    See identical proteins and their annotated locations for NP_659094.1

    Status: VALIDATED

    Source sequence(s)
    AC132893
    Consensus CDS
    CCDS27375.1
    UniProtKB/Swiss-Prot
    A1A4B4, Q3UP49, Q8JZZ0, Q8VC11
    Related
    ENSMUSP00000072236.7, ENSMUST00000072403.7
    Conserved Domains (2) summary
    PHA03392
    Location:235 → 488
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:23 → 488
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    9335670..9370960
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8JZZ0.2 GenPept UniProtKB/Swiss-Prot:Q8JZZ0

Gene LinkOut

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