U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TMEM218 transmembrane protein 218 [ Homo sapiens (human) ]

Gene ID: 219854, updated on 7-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
TMEM218provided by HGNC
Official Full Name
transmembrane protein 218provided by HGNC
Primary source
HGNC:HGNC:27344
See related
Ensembl:ENSG00000150433 MIM:619285; AllianceGenome:HGNC:27344
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
JBTS39
Summary
Predicted to be located in cilium. Predicted to be integral component of membrane. Implicated in Joubert syndrome. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in fat (RPKM 5.9), adrenal (RPKM 3.3) and 25 other tissues See more
Orthologs
mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
11q24.2
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (125094389..125111626, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (125123053..125140287, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (124964285..124981522, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:124823758-124824301 Neighboring gene coiled-coil domain containing 15 Neighboring gene MPRA-validated peak1499 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:124853252-124854004 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4036 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4037 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5692 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5693 Neighboring gene solute carrier family 37 member 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:124951446-124951995 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:124952423-124953622 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5694 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:124981662-124982574 Neighboring gene keratin 18 pseudogene 59 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:125011687-125012243 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4039 Neighboring gene PKNOX2 divergent transcript

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. TMEM218 dysfunction causes ciliopathies, including Joubert and Meckel syndromes. Van De Weghe JC, et al. HGG Adv, 2021 Jan 14. PMID 33791682, Free PMC Article
  2. The ciliary transition zone protein TMEM218 synergistically interacts with the NPHP module and its reduced dosage leads to a wide range of syndromic ciliopathies. Epting D, et al. Hum Mol Genet, 2022 Jul 21. PMID 35137054
  3. MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone. Li C, et al. PLoS Biol, 2016 Mar. PMID 26982032, Free PMC Article
  4. Systematic identification of pathological lamin A interactors. Dittmer TA, et al. Mol Biol Cell, 2014 May. PMID 24623722, Free PMC Article
  5. An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders. Chen S, et al. Nat Genet, 2018 Jul. PMID 29892012, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Joubert syndrome 39
MedGen: C5562000 OMIM: 619562 GeneReviews: Not available
Compare labs

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • DKFZp667A247

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cilium IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
transmembrane protein 218

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080546.3 → NP_001074015.1  transmembrane protein 218 isoform 2

    See identical proteins and their annotated locations for NP_001074015.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AA459752, AA781367, AP001007, BC132716, BC144277, BX094574, CX870447, DB194956
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48
    Related
    ENSP00000279968.4, ENST00000279968.8

  2. NM_001258238.2 → NP_001245167.1  transmembrane protein 218 isoform 2

    See identical proteins and their annotated locations for NP_001245167.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AA781367, AP001007, BC132716, BI829527, BX094574, CX870447
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  3. NM_001258239.3 → NP_001245168.2  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  4. NM_001258240.2 → NP_001245169.1  transmembrane protein 218 isoform 2

    See identical proteins and their annotated locations for NP_001245169.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AA781367, AP001007, BC132716, BM042315, BM928068, BX094574, CX870447, DA774499
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48
    Related
    ENSP00000436177.1, ENST00000526175.5

  5. NM_001258241.2 → NP_001245170.1  transmembrane protein 218 isoform 2

    See identical proteins and their annotated locations for NP_001245170.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AA781367, AP001007, BC132716, BM042315, BX094574, CX870447, DA774499
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48
    Related
    ENSP00000436162.1, ENST00000527271.5

  6. NM_001258242.3 → NP_001245171.2  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48
    Related
    ENSP00000436596.1, ENST00000531909.5

  7. NM_001258243.3 → NP_001245172.2  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 2. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48
    Related
    ENSP00000434597.1, ENST00000532407.5

  8. NM_001258244.2 → NP_001245173.1  transmembrane protein 218 isoform 2

    See identical proteins and their annotated locations for NP_001245173.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AA459752, AA781367, AP001007, BC132716, BE513148, BQ681518, BX094574, CX870447
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48
    Related
    ENSP00000506979.1, ENST00000682305.1

  9. NM_001258245.2 → NP_001245174.1  transmembrane protein 218 isoform 2

    See identical proteins and their annotated locations for NP_001245174.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AA459752, AA781367, AP001007, BC132716, BQ223298, BU855096, BX094574, CX870447
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48
    Related
    ENSP00000433374.1, ENST00000529583.5

  10. NM_001258246.3 → NP_001245175.2  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  11. NM_001258247.2 → NP_001245176.1  transmembrane protein 218 isoform 2

    See identical proteins and their annotated locations for NP_001245176.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AA459752, AA781367, AP001007, BC132716, BI856825, BX094574, CX870447
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48
    Related
    ENSP00000435526.1, ENST00000527766.5

  12. NM_001387230.1 → NP_001374159.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (19) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  13. NM_001387231.1 → NP_001374160.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (20) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  14. NM_001387232.1 → NP_001374161.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (21) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  15. NM_001387233.1 → NP_001374162.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (22) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  16. NM_001387234.1 → NP_001374163.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (23) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  17. NM_001387235.1 → NP_001374164.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (24) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  18. NM_001387236.1 → NP_001374165.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (25) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  19. NM_001387237.1 → NP_001374166.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (26) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  20. NM_001387238.1 → NP_001374167.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (27) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  21. NM_001387239.1 → NP_001374168.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (28) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  22. NM_001387240.1 → NP_001374169.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (29) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  23. NM_001387241.1 → NP_001374170.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (30) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  24. NM_001387242.1 → NP_001374171.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (31) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  25. NM_001387244.1 → NP_001374173.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (33) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  26. NM_001387245.1 → NP_001374174.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (34) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  27. NM_001387246.1 → NP_001374175.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (35) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  28. NM_001387247.1 → NP_001374176.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (36) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  29. NM_001387248.1 → NP_001374177.1  transmembrane protein 218 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (37) differs in the 5' UTR compared to variant 1. Variants 1-11 and 19-37 all encode the same isoform (2).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS31715.1
    UniProtKB/Swiss-Prot
    A2RU14, B7ZM48

  30. NM_001387249.1 → NP_001374178.1  transmembrane protein 218 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (38) encodes the longest isoform (3).
    Source sequence(s)
    AP001007
    Consensus CDS
    CCDS91617.1
    UniProtKB/TrEMBL
    E9PI23
    Related
    ENSP00000436578.1, ENST00000528724.5

  31. NM_001387250.1 → NP_001374179.1  transmembrane protein 218 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (39), as well as variants 40-43, encodes isoform 4.
    Source sequence(s)
    AP001007

  32. NM_001387251.1 → NP_001374180.1  transmembrane protein 218 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (40), as well as variants 39 and 41-43, encodes isoform 4.
    Source sequence(s)
    AP001007

  33. NM_001387252.1 → NP_001374181.1  transmembrane protein 218 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (41), as well as variants 39, 40, 42, and 43, encodes isoform 4.
    Source sequence(s)
    AP001007

  34. NM_001387253.1 → NP_001374182.1  transmembrane protein 218 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (42), as well as variants 39-41 and 43, encodes isoform 4.
    Source sequence(s)
    AP001007

  35. NM_001387254.1 → NP_001374183.1  transmembrane protein 218 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (43), as well as variants 39-42, encodes isoform 4.
    Source sequence(s)
    AP001007

  36. NM_001387255.1 → NP_001374184.1  transmembrane protein 218 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (44), as well as variants 45-48, encodes isoform 5.
    Source sequence(s)
    AP001007

  37. NM_001387256.1 → NP_001374185.1  transmembrane protein 218 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (45), as well as variants 44 and 46-48, encodes isoform 5.
    Source sequence(s)
    AP001007

  38. NM_001387257.1 → NP_001374186.1  transmembrane protein 218 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (46), as well as variants 44, 45, 47, and 48, encodes isoform 5.
    Source sequence(s)
    AP001007

  39. NM_001387258.1 → NP_001374187.1  transmembrane protein 218 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (47), as well as variants 44-46 and 48, encodes isoform 5.
    Source sequence(s)
    AP001007

  40. NM_001387259.1 → NP_001374188.1  transmembrane protein 218 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (48), as well as variants 44-47, encodes isoform 5.
    Source sequence(s)
    AP001007

RNA

  1. NR_047586.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12) has multiple differences, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
    Source sequence(s)
    AA781367, AP001007, BC132716, BI192743, BX094574, CX870447

  2. NR_047587.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (13) lacks several alternate 5' exons, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
    Source sequence(s)
    AA781367, AP001007, BC132716, BE974033, BX094574, CX870447, DA774499

  3. NR_047588.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (14) has multiple differences, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AA459752, AA781367, AP001007, BC132716, BC144276, BX094574, CX870447, DB194956

  4. NR_047589.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (15) has multiple differences, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
    Source sequence(s)
    AA459752, AA781367, AP001007, BQ225039, BX094574, CX870447

  5. NR_047590.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (16) has multiple differences, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
    Source sequence(s)
    AA459752, AA781367, AP001007, BC132716, BU598207, BX094574, CX870447

  6. NR_047591.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (17) has multiple differences, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
    Source sequence(s)
    AA459752, AA781367, AP001007, BC132716, BI547955, BX094574, CX870447

  7. NR_047592.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (18) has multiple differences, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
    Source sequence(s)
    AA459752, AA781367, AP001007, BC132716, BU160644, BU598207, BX094574, CX870447

  8. NR_170600.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

  9. NR_170601.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

  10. NR_170602.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

  11. NR_170603.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

  12. NR_170604.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

  13. NR_170605.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

  14. NR_170606.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

  15. NR_170607.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

  16. NR_170608.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

  17. NR_170609.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

  18. NR_170610.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

  19. NR_170611.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

  20. NR_170612.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

  21. NR_170613.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP001007

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    125094389..125111626 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047426541.1 → XP_047282497.1  transmembrane protein 218 isoform X1

  2. XM_047426543.1 → XP_047282499.1  transmembrane protein 218 isoform X1

  3. XM_047426540.1 → XP_047282496.1  transmembrane protein 218 isoform X1

  4. XM_047426542.1 → XP_047282498.1  transmembrane protein 218 isoform X1

  5. XM_006718780.4 → XP_006718843.1  transmembrane protein 218 isoform X1

    See identical proteins and their annotated locations for XP_006718843.1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    125123053..125140287 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054367985.1 → XP_054223960.1  transmembrane protein 218 isoform X1

  2. XM_054367987.1 → XP_054223962.1  transmembrane protein 218 isoform X1

  3. XM_054367986.1 → XP_054223961.1  transmembrane protein 218 isoform X1

  4. XM_054367988.1 → XP_054223963.1  transmembrane protein 218 isoform X1

  5. XM_054367984.1 → XP_054223959.1  transmembrane protein 218 isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2RU14.1 GenPept UniProtKB/Swiss-Prot:A2RU14

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous