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Zmym5 zinc finger, MYM-type 5 [ Mus musculus (house mouse) ]

Gene ID: 219105, updated on 8-Feb-2024

Summary

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Official Symbol
Zmym5provided by MGI
Official Full Name
zinc finger, MYM-type 5provided by MGI
Primary source
MGI:MGI:3041170
See related
Ensembl:ENSMUSG00000040123 AllianceGenome:MGI:3041170
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9830124H08Rik
Summary
Predicted to enable zinc ion binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in genitourinary system. Orthologous to human ZMYM5 (zinc finger MYM-type containing 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 7.9), CNS E11.5 (RPKM 6.6) and 27 other tissues See more
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Genomic context

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See Zmym5 in Genome Data Viewer
Location:
14 C3; 14 28.45 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (57028042..57049213, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (56790585..56815051, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene paraspeckle protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E9897 Neighboring gene predicted gene 4479 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene RIKEN cDNA 2410022M11 gene Neighboring gene STARR-positive B cell enhancer ABC_E5443 Neighboring gene STARR-seq mESC enhancer starr_36798 Neighboring gene predicted gene, 48906

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The nuclear localization pattern and interaction partners of GTF2IRD1 demonstrate a role in chromatin regulation. Carmona-Mora P, et al. Hum Genet, 2015 Oct. PMID 26275350
  2. Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation. Barnes CE, et al. Mol Omics, 2022 Jan 17. PMID 34709266, Free PMC Article
  3. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  5. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC38922

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger MYM-type protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001253752.1 → NP_001240681.1  zinc finger MYM-type protein 5

    See identical proteins and their annotated locations for NP_001240681.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-3 encode the same protein.
    Source sequence(s)
    AC154361
    Consensus CDS
    CCDS49505.1
    UniProtKB/Swiss-Prot
    Q3U2E2, Q8R1W3
    Related
    ENSMUSP00000043625.10, ENSMUST00000039812.16
    Conserved Domains (2) summary
    smart00597
    Location:528 → 603
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:343 → 381
    zf-FCS; MYM-type Zinc finger with FCS sequence motif

  2. NM_001253753.1 → NP_001240682.1  zinc finger MYM-type protein 5

    See identical proteins and their annotated locations for NP_001240682.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-3 encode the same protein.
    Source sequence(s)
    AC154361
    Consensus CDS
    CCDS49505.1
    UniProtKB/Swiss-Prot
    Q3U2E2, Q8R1W3
    Related
    ENSMUSP00000134057.2, ENSMUST00000173954.3
    Conserved Domains (2) summary
    smart00597
    Location:528 → 603
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:343 → 381
    zf-FCS; MYM-type Zinc finger with FCS sequence motif

  3. NM_144842.4 → NP_659091.3  zinc finger MYM-type protein 5

    See identical proteins and their annotated locations for NP_659091.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1), and variants 2 and 3 encode the same protein.
    Source sequence(s)
    AC154361
    Consensus CDS
    CCDS49505.1
    UniProtKB/Swiss-Prot
    Q3U2E2, Q8R1W3
    Related
    ENSMUSP00000106916.3, ENSMUST00000111285.9
    Conserved Domains (2) summary
    smart00597
    Location:528 → 603
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:343 → 381
    zf-FCS; MYM-type Zinc finger with FCS sequence motif

RNA

  1. NR_136882.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC154361, AK036513

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    57028042..57049213 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006518852.5 → XP_006518915.2  zinc finger MYM-type protein 5 isoform X1

    UniProtKB/Swiss-Prot
    Q3U2E2, Q8R1W3
    Conserved Domains (2) summary
    smart00597
    Location:528 → 603
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:343 → 381
    zf-FCS; MYM-type Zinc finger with FCS sequence motif

  2. XM_011245022.3 → XP_011243324.1  zinc finger MYM-type protein 5 isoform X1

    See identical proteins and their annotated locations for XP_011243324.1

    UniProtKB/Swiss-Prot
    Q3U2E2, Q8R1W3
    Conserved Domains (2) summary
    smart00597
    Location:528 → 603
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:343 → 381
    zf-FCS; MYM-type Zinc finger with FCS sequence motif

  3. XM_036158560.1 → XP_036014453.1  zinc finger MYM-type protein 5 isoform X1

    UniProtKB/Swiss-Prot
    Q3U2E2, Q8R1W3
    Conserved Domains (2) summary
    smart00597
    Location:528 → 603
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:343 → 381
    zf-FCS; MYM-type Zinc finger with FCS sequence motif

  4. XM_030247759.2 → XP_030103619.1  zinc finger MYM-type protein 5 isoform X1

    UniProtKB/Swiss-Prot
    Q3U2E2, Q8R1W3
    Conserved Domains (2) summary
    smart00597
    Location:528 → 603
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:343 → 381
    zf-FCS; MYM-type Zinc finger with FCS sequence motif

  5. XM_017315967.2 → XP_017171456.1  zinc finger MYM-type protein 5 isoform X1

    UniProtKB/Swiss-Prot
    Q3U2E2, Q8R1W3
    Conserved Domains (2) summary
    smart00597
    Location:528 → 603
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:343 → 381
    zf-FCS; MYM-type Zinc finger with FCS sequence motif

  6. XM_006518857.3 → XP_006518920.1  zinc finger MYM-type protein 5 isoform X1

    See identical proteins and their annotated locations for XP_006518920.1

    UniProtKB/Swiss-Prot
    Q3U2E2, Q8R1W3
    Conserved Domains (2) summary
    smart00597
    Location:528 → 603
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:343 → 381
    zf-FCS; MYM-type Zinc finger with FCS sequence motif

  7. XM_030247761.2 → XP_030103621.1  zinc finger MYM-type protein 5 isoform X1

    UniProtKB/Swiss-Prot
    Q3U2E2, Q8R1W3
    Conserved Domains (2) summary
    smart00597
    Location:528 → 603
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:343 → 381
    zf-FCS; MYM-type Zinc finger with FCS sequence motif
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3U2E2.2 GenPept UniProtKB/Swiss-Prot:Q3U2E2

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