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Tle2 transducin-like enhancer of split 2 [ Mus musculus (house mouse) ]

Gene ID: 21886, updated on 11-Apr-2024

Summary

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Official Symbol
Tle2provided by MGI
Official Full Name
transducin-like enhancer of split 2provided by MGI
Primary source
MGI:MGI:104635
See related
Ensembl:ENSMUSG00000034771 AllianceGenome:MGI:104635
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Grg2; Gm32024; mKIAA4188
Summary
Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway and negative regulation of transcription, DNA-templated. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in focal adhesion and nuclear body. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; integumental system; limb; and sensory organ. Orthologous to human TLE2 (TLE family member 2, transcriptional corepressor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in adrenal adult (RPKM 114.6), ovary adult (RPKM 111.1) and 21 other tissues See more
Orthologs
human all
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Genomic context

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Location:
10; 10 C1
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (81410573..81435018)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (81574739..81592581)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene TLE family member 5, transcriptional modulator Neighboring gene STARR-positive B cell enhancer ABC_E3902 Neighboring gene predicted gene, 31936 Neighboring gene transducin-like enhancer of split 6 Neighboring gene STARR-positive B cell enhancer ABC_E9796 Neighboring gene STARR-positive B cell enhancer ABC_E2953 Neighboring gene STARR-positive B cell enhancer ABC_E464 Neighboring gene zinc finger protein pseudogene Neighboring gene STARR-seq mESC enhancer starr_27345 Neighboring gene STARR-positive B cell enhancer ABC_E6888 Neighboring gene sirtuin 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The E2A-HLF oncoprotein activates Groucho-related genes and suppresses Runx1. Dang J, et al. Mol Cell Biol, 2001 Sep. PMID 11486032, Free PMC Article
  2. TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination. Dehni G, et al. Mech Dev, 1995 Nov. PMID 8645603
  3. Transducin-like Enhancer of split 2, a mammalian homologue of Drosophila Groucho, acts as a transcriptional repressor, interacts with Hairy/Enhancer of split proteins, and is expressed during neuronal development. Grbavec D, et al. Eur J Biochem, 1998 Dec 1. PMID 9874198
  4. Protein characterization and targeted disruption of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex. Mallo M, et al. Dev Dyn, 1995 Nov. PMID 8573724
  5. A Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression. Kaltenbrun E, et al. J Proteome Res, 2013 Dec 6. PMID 24024827, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA4188

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription corepressor activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of canonical Wnt signaling pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in focal adhesion ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription regulator complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
transducin-like enhancer protein 2
Names
groucho-related protein
transducin-like enhancer of split 2, homolog of Drosophila E(spl)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252401.2 → NP_001239330.1  transducin-like enhancer protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001239330.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses different splice sites in two locations in the coding region, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1.
    Source sequence(s)
    AC153919, AC159474
    Consensus CDS
    CCDS56737.1
    UniProtKB/TrEMBL
    E9PV07, Q3UN01
    Related
    ENSMUSP00000117453.2, ENSMUST00000135211.8
    Conserved Domains (4) summary
    COG2319
    Location:444 → 730
    WD40; WD40 repeat [General function prediction only]
    pfam03920
    Location:1 → 113
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    sd00039
    Location:449 → 488
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:445 → 729
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. NM_001428852.1 → NP_001415781.1  transducin-like enhancer protein 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC153919, AC159474

  3. NM_001428853.1 → NP_001415782.1  transducin-like enhancer protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC153919, AC159474

  4. NM_019725.3 → NP_062699.1  transducin-like enhancer protein 2 isoform 1

    See identical proteins and their annotated locations for NP_062699.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC153919, AC159474
    Consensus CDS
    CCDS24063.1
    UniProtKB/Swiss-Prot
    Q9WVB2
    UniProtKB/TrEMBL
    E9PV07
    Related
    ENSMUSP00000121125.2, ENSMUST00000146358.8
    Conserved Domains (4) summary
    PHA03247
    Location:269 → 459
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:484 → 523
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:480 → 764
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    81410573..81435018
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011243429.3 → XP_011241731.1  transducin-like enhancer protein 2 isoform X5

    See identical proteins and their annotated locations for XP_011241731.1

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:269 → 459
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:484 → 523
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:466 → 723
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_011243434.3 → XP_011241736.1  transducin-like enhancer protein 2 isoform X8

    See identical proteins and their annotated locations for XP_011241736.1

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:246 → 436
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:461 → 500
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 129
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:443 → 700
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_036155761.1 → XP_036011654.1  transducin-like enhancer protein 2 isoform X13

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:246 → 423
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:448 → 487
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:10 → 129
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:430 → 687
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_017313923.3 → XP_017169412.1  transducin-like enhancer protein 2 isoform X27

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:269 → 459
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:484 → 523
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:473 → 641
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  5. XM_011243425.4 → XP_011241727.1  transducin-like enhancer protein 2 isoform X1

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:269 → 458
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:483 → 522
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:465 → 722
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  6. XM_011243427.4 → XP_011241729.1  transducin-like enhancer protein 2 isoform X3

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:269 → 447
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:472 → 511
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:454 → 711
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  7. XM_011243428.4 → XP_011241730.1  transducin-like enhancer protein 2 isoform X4

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:269 → 446
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:471 → 510
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:453 → 710
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  8. XM_011243426.4 → XP_011241728.1  transducin-like enhancer protein 2 isoform X2

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:268 → 458
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:483 → 522
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 151
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:465 → 722
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  9. XM_011243430.4 → XP_011241732.1  transducin-like enhancer protein 2 isoform X6

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:248 → 438
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:463 → 502
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 131
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:445 → 702
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  10. XM_011243431.4 → XP_011241733.1  transducin-like enhancer protein 2 isoform X7

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:247 → 437
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:462 → 501
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 130
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:444 → 701
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  11. XM_036155764.1 → XP_036011657.1  transducin-like enhancer protein 2 isoform X31

    Conserved Domains (2) summary
    sd00039
    Location:81 → 120
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:70 → 320
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  12. XM_030245058.2 → XP_030100918.1  transducin-like enhancer protein 2 isoform X32

    Conserved Domains (2) summary
    sd00039
    Location:67 → 106
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:56 → 306
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  13. XM_011243432.4 → XP_011241734.1  transducin-like enhancer protein 2 isoform X8

    See identical proteins and their annotated locations for XP_011241734.1

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:246 → 436
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:461 → 500
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 129
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:443 → 700
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  14. XM_030245051.2 → XP_030100911.1  transducin-like enhancer protein 2 isoform X9

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:246 → 435
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:460 → 499
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 129
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:442 → 699
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  15. XM_030245052.2 → XP_030100912.1  transducin-like enhancer protein 2 isoform X12

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:246 → 424
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:449 → 488
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 129
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:431 → 688
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  16. XM_011243433.4 → XP_011241735.1  transducin-like enhancer protein 2 isoform X13

    UniProtKB/TrEMBL
    E9PV07
    Related
    ENSMUSP00000121173.2, ENSMUST00000146916.8
    Conserved Domains (4) summary
    PHA03247
    Location:246 → 423
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:448 → 487
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:10 → 129
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:430 → 687
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  17. XM_017313919.3 → XP_017169408.1  transducin-like enhancer protein 2 isoform X10

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:245 → 435
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:460 → 499
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 128
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:442 → 699
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  18. XM_017313920.3 → XP_017169409.1  transducin-like enhancer protein 2 isoform X11

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:245 → 434
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:459 → 498
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 128
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:441 → 698
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  19. XM_017313921.3 → XP_017169410.1  transducin-like enhancer protein 2 isoform X14

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:245 → 422
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:447 → 486
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 128
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:429 → 686
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  20. XM_036155763.1 → XP_036011656.1  transducin-like enhancer protein 2 isoform X30

    Conserved Domains (2) summary
    sd00039
    Location:93 → 132
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:82 → 332
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  21. XM_011243435.4 → XP_011241737.1  transducin-like enhancer protein 2 isoform X15

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:225 → 415
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:440 → 479
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 108
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:422 → 679
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  22. XM_006513584.4 → XP_006513647.1  transducin-like enhancer protein 2 isoform X16

    See identical proteins and their annotated locations for XP_006513647.1

    UniProtKB/Swiss-Prot
    Q9WVB2
    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:269 → 459
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:484 → 523
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:480 → 764
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  23. XM_006513585.4 → XP_006513648.1  transducin-like enhancer protein 2 isoform X17

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:269 → 458
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:483 → 522
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:479 → 763
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  24. XM_030245053.2 → XP_030100913.1  transducin-like enhancer protein 2 isoform X18

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:269 → 447
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:472 → 511
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:468 → 752
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  25. XM_017313922.3 → XP_017169411.1  transducin-like enhancer protein 2 isoform X19

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:269 → 446
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:471 → 510
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:467 → 751
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  26. XM_030245059.2 → XP_030100919.1  transducin-like enhancer protein 2 isoform X33

    UniProtKB/TrEMBL
    Q5DTI7
    Related
    ENSMUST00000140433.8
    Conserved Domains (2) summary
    sd00039
    Location:93 → 132
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:89 → 373
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  27. XM_006513589.5 → XP_006513652.1  transducin-like enhancer protein 2 isoform X34

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:246 → 435
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:460 → 499
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 129
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:456 → 740
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  28. XM_030245055.2 → XP_030100915.1  transducin-like enhancer protein 2 isoform X22

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:246 → 424
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:449 → 488
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 129
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:445 → 729
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  29. XM_030245056.2 → XP_030100916.1  transducin-like enhancer protein 2 isoform X23

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:246 → 423
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:448 → 487
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 129
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:444 → 728
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  30. XM_011243436.4 → XP_011241738.1  transducin-like enhancer protein 2 isoform X21

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:245 → 434
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:459 → 498
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 128
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:455 → 739
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  31. XM_030245057.2 → XP_030100917.1  transducin-like enhancer protein 2 isoform X24

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:245 → 422
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:447 → 486
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 128
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:443 → 727
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  32. XM_030245060.2 → XP_030100920.1  transducin-like enhancer protein 2 isoform X35

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:225 → 414
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:439 → 478
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 108
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:435 → 719
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  33. XM_006513586.4 → XP_006513649.1  transducin-like enhancer protein 2 isoform X25

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:269 → 459
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:484 → 523
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:466 → 711
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  34. XM_036155762.1 → XP_036011655.1  transducin-like enhancer protein 2 isoform X26

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:269 → 446
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:471 → 510
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:10 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:453 → 698
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  35. XM_006513588.5 → XP_006513651.1  transducin-like enhancer protein 2 isoform X28

    Conserved Domains (3) summary
    smart00320
    Location:473 → 508
    WD40; WD40 repeats
    PHA03247
    Location:269 → 460
    PHA03247; large tegument protein UL36; Provisional
    pfam03920
    Location:1 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain

  36. XM_017313924.3 → XP_017169413.1  transducin-like enhancer protein 2 isoform X29

    Conserved Domains (3) summary
    smart00320
    Location:472 → 507
    WD40; WD40 repeats
    PHA03247
    Location:269 → 459
    PHA03247; large tegument protein UL36; Provisional
    pfam03920
    Location:1 → 152
    TLE_N; Groucho/TLE N-terminal Q-rich domain

  37. XM_030245054.2 → XP_030100914.1  transducin-like enhancer protein 2 isoform X20

    UniProtKB/TrEMBL
    E9PV07
    Conserved Domains (4) summary
    PHA03247
    Location:193 → 383
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:408 → 447
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:24 → 76
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:390 → 647
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

  1. XR_004936169.1 RNA Sequence

  2. XR_380389.5 RNA Sequence

  3. XR_003948682.2 RNA Sequence

  4. XR_004936170.1 RNA Sequence

  5. XR_380390.5 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9WVB2.1 GenPept UniProtKB/Swiss-Prot:Q9WVB2

Gene LinkOut

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