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Tex2 testis expressed gene 2 [ Mus musculus (house mouse) ]

Gene ID: 21763, updated on 21-Apr-2024

Summary

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Official Symbol
Tex2provided by MGI
Official Full Name
testis expressed gene 2provided by MGI
Primary source
MGI:MGI:102465
See related
Ensembl:ENSMUSG00000040548 AllianceGenome:MGI:102465
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Taz4; Def-5; 4930568E07Rik
Summary
Predicted to enable lipid binding activity. Predicted to act upstream of or within lipid transport. Predicted to be located in membrane and nucleus. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; genitourinary system; liver; nervous system; and respiratory system. Orthologous to human TEX2 (testis expressed 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 83.3), placenta adult (RPKM 18.2) and 19 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 E1; 11 69.46 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (106392965..106504259, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (106502139..106613433, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, C/D box 104 Neighboring gene predicted gene, 36220 Neighboring gene predicted gene, 22711 Neighboring gene nucleophosmin 1 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:106397706-106397815 Neighboring gene STARR-seq mESC enhancer starr_30931 Neighboring gene STARR-positive B cell enhancer ABC_E5288 Neighboring gene STARR-positive B cell enhancer ABC_E1150 Neighboring gene platelet/endothelial cell adhesion molecule 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:106535909-106536110 Neighboring gene STARR-seq mESC enhancer starr_30943 Neighboring gene STARR-seq mESC enhancer starr_30946 Neighboring gene predicted gene, 51950

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Def-2, -3, -6 and -8, novel mouse genes differentially expressed in the haemopoietic system. Hotfilder M, et al. Br J Haematol, 1999 Aug. PMID 10460589
  2. Chromosomal assignment of three novel mouse genes expressed in testicular cells. Lemaire L, et al. Genomics, 1994 May 15. PMID 8088835
  3. Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9. Bronson RT, et al. Am J Med Genet, 1998 May 26. PMID 9600738
  4. Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Munton RP, et al. Mol Cell Proteomics, 2007 Feb. PMID 17114649
  5. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Federspiel JD, et al. Mol Cell Proteomics, 2019 Aug 9. PMID 31040226, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables lipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
acts_upstream_of_or_within lipid transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
testis-expressed protein 2
Names
testis-expressed sequence 2 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198292.3 → NP_938034.2  testis-expressed protein 2

    See identical proteins and their annotated locations for NP_938034.2

    Status: VALIDATED

    Source sequence(s)
    AK129434, BY667615, CB594125
    Consensus CDS
    CCDS25557.1
    UniProtKB/Swiss-Prot
    B1ATR1, Q6ZPJ0
    Related
    ENSMUSP00000041985.8, ENSMUST00000042780.14
    Conserved Domains (1) summary
    pfam10296
    Location:826 → 915
    DUF2404; Putative integral membrane protein conserved region (DUF2404)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    106392965..106504259 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156623.1 → XP_036012516.1  testis-expressed protein 2 isoform X2

  2. XM_006533145.2 → XP_006533208.1  testis-expressed protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006533208.1

    UniProtKB/Swiss-Prot
    B1ATR1, Q6ZPJ0
    Conserved Domains (1) summary
    pfam10296
    Location:826 → 915
    DUF2404; Putative integral membrane protein conserved region (DUF2404)

  3. XM_036156622.1 → XP_036012515.1  testis-expressed protein 2 isoform X2

  4. XM_006533146.5 → XP_006533209.1  testis-expressed protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006533209.1

    UniProtKB/Swiss-Prot
    B1ATR1, Q6ZPJ0
    Conserved Domains (1) summary
    pfam10296
    Location:826 → 915
    DUF2404; Putative integral membrane protein conserved region (DUF2404)

  5. XM_006533148.5 → XP_006533211.1  testis-expressed protein 2 isoform X2

    Conserved Domains (1) summary
    pfam10296
    Location:826 → 915
    DUF2404; Putative integral membrane protein conserved region (DUF2404)

  6. XM_036156621.1 → XP_036012514.1  testis-expressed protein 2 isoform X1

    UniProtKB/Swiss-Prot
    B1ATR1, Q6ZPJ0

  7. XM_006533147.4 → XP_006533210.1  testis-expressed protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006533210.1

    UniProtKB/Swiss-Prot
    B1ATR1, Q6ZPJ0
    Conserved Domains (1) summary
    pfam10296
    Location:826 → 915
    DUF2404; Putative integral membrane protein conserved region (DUF2404)

  8. XM_006533144.4 → XP_006533207.1  testis-expressed protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006533207.1

    UniProtKB/Swiss-Prot
    B1ATR1, Q6ZPJ0
    Conserved Domains (1) summary
    pfam10296
    Location:826 → 915
    DUF2404; Putative integral membrane protein conserved region (DUF2404)

  9. XM_006533143.4 → XP_006533206.1  testis-expressed protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006533206.1

    UniProtKB/Swiss-Prot
    B1ATR1, Q6ZPJ0
    Conserved Domains (1) summary
    pfam10296
    Location:826 → 915
    DUF2404; Putative integral membrane protein conserved region (DUF2404)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6ZPJ0.2 GenPept UniProtKB/Swiss-Prot:Q6ZPJ0

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