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Myo15b myosin XVB [ Mus musculus (house mouse) ]

Gene ID: 217328, updated on 5-Mar-2024

Summary

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Official Symbol
Myo15bprovided by MGI
Official Full Name
myosin XVBprovided by MGI
Primary source
MGI:MGI:2685534
See related
Ensembl:ENSMUSG00000034427 AllianceGenome:MGI:2685534
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm688; Gm886; mKIAA1783; E330039G21Rik
Summary
Located in brush border. Is expressed in genitourinary system. Orthologous to human MYO15B (myosin XVB). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in small intestine adult (RPKM 116.1), colon adult (RPKM 107.2) and 3 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 E2; 11 80.91 cM
Exon count:
66
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (115749002..115783443)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (115857925..115892617)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3039 Neighboring gene tRNA splicing endonuclease subunit 54 Neighboring gene STARR-seq mESC enhancer starr_31175 Neighboring gene LLGL2 scribble cell polarity complex component Neighboring gene STARR-seq mESC enhancer starr_31178 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:115759828-115760025 Neighboring gene RecQ protein-like 5 Neighboring gene small integral membrane protein 5 Neighboring gene small integral membrane protein 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Human myosin XVBP is a transcribed pseudogene. Boger ET, et al. J Muscle Res Cell Motil, 2001. PMID 11964073
  2. Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules. Georgas KM, et al. Dev Dyn, 2011 Jun. PMID 21491542, Free PMC Article
  3. A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins. Revenu C, et al. Mol Biol Cell, 2012 Jan. PMID 22114352, Free PMC Article
  4. Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. Thiagarajan RD, et al. PLoS One, 2011 Feb 28. PMID 21386911, Free PMC Article
  5. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in brush border IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
myosin XVB

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001384233.2 → NP_001371162.1  myosin XVB

    Status: VALIDATED

    Source sequence(s)
    AL645647
    UniProtKB/TrEMBL
    I7HPW8
    Related
    ENSMUSP00000091439.6, ENSMUST00000093911.11
    Conserved Domains (8) summary
    PTZ00449
    Location:185 → 326
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd14896
    Location:681 → 1360
    MYSc_Myo35; class XXXV myosin, motor domain
    pfam00373
    Location:2859 → 2968
    FERM_M; FERM central domain
    pfam00784
    Location:1575 → 1677
    MyTH4; MyTH4 domain
    cl02480
    Location:2617 → 2763
    MyTH4; MyTH4 domain
    cl17036
    Location:2469 → 2523
    SH3; Src Homology 3 domain superfamily
    cl17171
    Location:2964 → 3064
    PH-like; Pleckstrin homology-like domain
    cl28922
    Location:2784 → 2839
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    115749002..115783443
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156604.1 → XP_036012497.1  myosin XVB isoform X1

    UniProtKB/TrEMBL
    A0A1Y7VNG3
    Related
    ENSMUSP00000152405.2, ENSMUST00000222123.2
    Conserved Domains (6) summary
    pfam00373
    Location:1401 → 1510
    FERM_M; FERM central domain
    pfam00784
    Location:117 → 219
    MyTH4; MyTH4 domain
    cl02480
    Location:1159 → 1305
    MyTH4; MyTH4 domain
    cl17036
    Location:1011 → 1065
    SH3; Src Homology 3 domain superfamily
    cl17171
    Location:1506 → 1606
    PH-like; Pleckstrin homology-like domain
    cl28922
    Location:1326 → 1381
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
Nucleotide Protein Strain
Heading Accession and Version

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