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Fam171a2 family with sequence similarity 171, member A2 [ Mus musculus (house mouse) ]

Gene ID: 217219, updated on 5-Mar-2024

Summary

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Official Symbol
Fam171a2provided by MGI
Official Full Name
family with sequence similarity 171, member A2provided by MGI
Primary source
MGI:MGI:2448496
See related
Ensembl:ENSMUSG00000034685 AllianceGenome:MGI:2448496
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human FAM171A2 (family with sequence similarity 171 member A2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in whole brain E14.5 (RPKM 63.7), CNS E18 (RPKM 59.6) and 16 other tissues See more
Orthologs
human all
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Genomic context

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See Fam171a2 in Genome Data Viewer
Location:
11 D; 11 66.29 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (102327807..102338551, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (102436981..102447677, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5282 Neighboring gene solute carrier family 25, member 39 Neighboring gene STARR-seq mESC enhancer starr_30808 Neighboring gene microRNA 6930 Neighboring gene STARR-positive B cell enhancers ABC_E9375 and ABC_E8457 Neighboring gene granulin Neighboring gene integrin alpha 2b Neighboring gene STARR-positive B cell enhancer ABC_E7070 Neighboring gene G patch domain containing 8 Neighboring gene cytochrome b-c1 complex subunit 10 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Li J, et al. Nat Neurosci, 2017 Aug. PMID 28671696, Free PMC Article
  2. Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies. Murtaza N, et al. Cell Rep, 2022 Nov 22. PMID 36417873
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein FAM171A2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199200.2 → NP_954670.2  protein FAM171A2 precursor

    See identical proteins and their annotated locations for NP_954670.2

    Status: VALIDATED

    Source sequence(s)
    AL596258, CB182176, CB202938, CJ162493
    Consensus CDS
    CCDS36344.1
    UniProtKB/Swiss-Prot
    A2A699, B7ZC48, Q05CH6, Q6P2L1
    Related
    ENSMUSP00000038486.5, ENSMUST00000049057.5
    Conserved Domains (1) summary
    pfam10577
    Location:41 → 820
    UPF0560; uncharacterized protein family UPF0560

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    102327807..102338551 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006533049.5 → XP_006533112.1  protein FAM171A2 isoform X1

    Conserved Domains (1) summary
    pfam10577
    Location:41 → 813
    UPF0560; Uncharacterized protein family UPF0560
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2A699.1 GenPept UniProtKB/Swiss-Prot:A2A699

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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