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Spata20 spermatogenesis associated 20 [ Mus musculus (house mouse) ]

Gene ID: 217116, updated on 5-Mar-2024

Summary

Official Symbol
Spata20provided by MGI
Official Full Name
spermatogenesis associated 20provided by MGI
Primary source
MGI:MGI:2183449
See related
Ensembl:ENSMUSG00000020867 AllianceGenome:MGI:2183449
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tisp78
Summary
Predicted to be involved in carbohydrate metabolic process. Predicted to act upstream of or within cell differentiation and spermatogenesis. Predicted to be located in extracellular region. Used to study oligoasthenoteratozoospermia. Orthologous to human SPATA20 (spermatogenesis associated 20). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 496.0) See more
Orthologs
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Genomic context

Location:
11 D; 11 58.9 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (94369730..94376136, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (94478904..94485310, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette, sub-family C member 3 Neighboring gene predicted gene, 51871 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:94235659-94235882 Neighboring gene STARR-seq mESC enhancer starr_30466 Neighboring gene STARR-seq mESC enhancer starr_30467 Neighboring gene calcium channel, voltage-dependent, T type, alpha 1G subunit Neighboring gene STARR-seq mESC enhancer starr_30468 Neighboring gene predicted gene, 51872 Neighboring gene STARR-positive B cell enhancer ABC_E10707 Neighboring gene epsin 3 Neighboring gene predicted gene, 51873 Neighboring gene MYCBP associated protein Neighboring gene predicted gene, 35650

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
spermatogenesis-associated protein 20
Names
sperm protein SSP411
sperm-specific protein 411
ssp411
transcript increased in spermiogenesis 78 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144827.4NP_659076.2  spermatogenesis-associated protein 20

    See identical proteins and their annotated locations for NP_659076.2

    Status: VALIDATED

    Source sequence(s)
    BC050788
    Consensus CDS
    CCDS25256.1
    UniProtKB/Swiss-Prot
    Q80YT5
    Related
    ENSMUSP00000042572.8, ENSMUST00000041705.8
    Conserved Domains (3) summary
    COG1331
    Location:59788
    YyaL; Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains [General function prediction only]
    pfam03190
    Location:67227
    Thioredox_DsbH; Protein of unknown function, DUF255
    pfam06202
    Location:595637
    GDE_C; Amylo-alpha-1,6-glucosidase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    94369730..94376136 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)