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Proca1 protein interacting with cyclin A1 [ Mus musculus (house mouse) ]

Gene ID: 216974, updated on 5-Mar-2024

Summary

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Official Symbol
Proca1provided by MGI
Official Full Name
protein interacting with cyclin A1provided by MGI
Primary source
MGI:MGI:1918274
See related
Ensembl:ENSMUSG00000044122 AllianceGenome:MGI:1918274
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4933404M19Rik
Summary
Predicted to enable cyclin binding activity. Orthologous to human PROCA1 (protein interacting with cyclin A1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 38.8) and subcutaneous fat pad adult (RPKM 1.4) See more
Orthologs
human all
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Genomic context

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See Proca1 in Genome Data Viewer
Location:
11 B5; 11 46.74 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (78083086..78096589)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (78192677..78205763)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5250 Neighboring gene ribosomal protein L23A Neighboring gene small nucleolar RNA, C/D box 42B Neighboring gene Rab34 Hedgehog-responsive enhancer Neighboring gene RAB34, member RAS oncogene family Neighboring gene SPT6, histone chaperone and transcription elongation factor Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:78029402-78029555 Neighboring gene STARR-seq mESC enhancer starr_30092 Neighboring gene stromal cell derived factor 2 Neighboring gene small nuclear ribonucleoprotein N pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cyclin binding ISO
Inferred from Sequence Orthology
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables phospholipase A2 activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in arachidonic acid secretion IEA
Inferred from Electronic Annotation
more info
  
involved_in biological_process ND
No biological Data available
more info
  
involved_in phospholipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein PROCA1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045516.2 → NP_001038981.2  protein PROCA1 isoform 2

    See identical proteins and their annotated locations for NP_001038981.2

    Status: VALIDATED

    Source sequence(s)
    AK160258, AL591070, BY648103
    Consensus CDS
    CCDS36238.1
    UniProtKB/TrEMBL
    B0QZF6
    Related
    ENSMUSP00000086022.3, ENSMUST00000078099.4
    Conserved Domains (1) summary
    cl05417
    Location:1 → 36
    PLA2_like; Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a ...

  2. NM_001368876.1 → NP_001355805.1  protein PROCA1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL591070
    Consensus CDS
    CCDS88201.1
    UniProtKB/Swiss-Prot
    B0QZF7
    Related
    ENSMUSP00000103953.3, ENSMUST00000108317.3
    Conserved Domains (1) summary
    cd04705
    Location:30 → 123
    PLA2_group_III_like; A sub-family of Phospholipase A2, similar to human group III PLA2. PLA2 is a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position of the glycerol ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    78083086..78096589
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030245840.2 → XP_030101700.1  protein PROCA1 isoform X1

    UniProtKB/TrEMBL
    B0QZF6
    Conserved Domains (1) summary
    cl05417
    Location:1 → 36
    PLA2_like; Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a ...

  2. XM_036156580.1 → XP_036012473.1  protein PROCA1 isoform X1

    UniProtKB/TrEMBL
    B0QZF6
    Conserved Domains (1) summary
    cl05417
    Location:1 → 36
    PLA2_like; Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a ...

  3. XM_036156581.1 → XP_036012474.1  protein PROCA1 isoform X1

    UniProtKB/TrEMBL
    B0QZF6
    Conserved Domains (1) summary
    cl05417
    Location:1 → 36
    PLA2_like; Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B0QZF7.1 GenPept UniProtKB/Swiss-Prot:B0QZF7

Gene LinkOut

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