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Fam222b family with sequence similarity 222, member B [ Mus musculus (house mouse) ]

Gene ID: 216971, updated on 5-Mar-2024

Summary

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Official Symbol
Fam222bprovided by MGI
Official Full Name
family with sequence similarity 222, member Bprovided by MGI
Primary source
MGI:MGI:2384939
See related
Ensembl:ENSMUSG00000037750 AllianceGenome:MGI:2384939
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9630020I17Rik
Summary
Predicted to be located in nucleoplasm. Is expressed in central nervous system and retina. Orthologous to human FAM222B (family with sequence similarity 222 member B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 11.6), ovary adult (RPKM 11.1) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 B5; 11 46.74 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (77985516..78048165)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (78094690..78157339)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 57805 Neighboring gene microRNA 451a Neighboring gene microRNA 451b Neighboring gene Era like 12S mitochondrial rRNA chaperone 1 Neighboring gene STARR-seq mESC enhancer starr_30086 Neighboring gene U6 small nuclear RNA associated LSM6 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E10694 Neighboring gene STARR-seq mESC enhancer starr_30088 Neighboring gene TNF receptor associated factor 4 Neighboring gene STARR-positive B cell enhancer ABC_E8429 Neighboring gene STARR-positive B cell enhancer ABC_E9831 Neighboring gene NIMA (never in mitosis gene a)-related expressed kinase 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  2. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  3. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC28990

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein FAM222B
Names
uncharacterized protein C17orf63 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001346762.2 → NP_001333691.1  protein FAM222B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK047860, AL591070
    Consensus CDS
    CCDS83851.1
    UniProtKB/TrEMBL
    E9PXL0
    Related
    ENSMUSP00000126620.2, ENSMUST00000100782.4
    Conserved Domains (1) summary
    pfam15258
    Location:1 → 434
    FAM222A; Protein family of FAM222A

  2. NM_001364110.1 → NP_001351039.1  protein FAM222B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL591070, AL669840
    Consensus CDS
    CCDS25089.1
    UniProtKB/Swiss-Prot
    Q3UV50, Q6P539, Q8VD11
    Related
    ENSMUSP00000121832.2, ENSMUST00000155571.2
    Conserved Domains (1) summary
    pfam15258
    Location:27 → 561
    FAM222A; Protein family of FAM222A

  3. NM_145430.3 → NP_663405.1  protein FAM222B isoform 1

    See identical proteins and their annotated locations for NP_663405.1

    Status: VALIDATED

    Source sequence(s)
    AK085728, AK141119, AL591070, BE332328
    Consensus CDS
    CCDS25089.1
    UniProtKB/Swiss-Prot
    Q3UV50, Q6P539, Q8VD11
    Related
    ENSMUSP00000073384.6, ENSMUST00000073705.12
    Conserved Domains (1) summary
    pfam15258
    Location:27 → 561
    FAM222A; Protein family of FAM222A

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    77985516..78048165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030245839.2 → XP_030101699.1  protein FAM222B isoform X1

    UniProtKB/TrEMBL
    E9PXL0
    Conserved Domains (1) summary
    pfam15258
    Location:1 → 434
    FAM222A; Protein family of FAM222A
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P539.2 GenPept UniProtKB/Swiss-Prot:Q6P539

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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