U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rab3ip RAB3A interacting protein [ Mus musculus (house mouse) ]

Gene ID: 216363, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Rab3ipprovided by MGI
Official Full Name
RAB3A interacting proteinprovided by MGI
Primary source
MGI:MGI:105933
See related
Ensembl:ENSMUSG00000064181 AllianceGenome:MGI:105933
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rabin3; Gtpat12; B230311A06
Summary
Predicted to enable GTPase binding activity; guanyl-nucleotide exchange factor activity; and identical protein binding activity. Predicted to be involved in several processes, including cilium assembly; negative regulation of filopodium assembly; and protein targeting to membrane. Predicted to act upstream of or within protein transport. Predicted to be located in several cellular components, including centrosome; perinuclear region of cytoplasm; and proximal dendrite. Predicted to be active in Golgi to plasma membrane transport vesicle. Predicted to colocalize with Golgi apparatus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and respiratory system. Orthologous to human RAB3IP (RAB3A interacting protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in kidney adult (RPKM 46.3), testis adult (RPKM 22.8) and 26 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Rab3ip in Genome Data Viewer
Location:
10 D2; 10 64.96 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (116741685..116786361, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (116905780..116950456, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930579P08 gene Neighboring gene STARR-positive B cell enhancer mm9_chr10:116183775-116184076 Neighboring gene myelin regulatory factor-like Neighboring gene STARR-seq mESC enhancer starr_27965 Neighboring gene STARR-seq mESC enhancer starr_27966 Neighboring gene STARR-seq mESC enhancer starr_27967 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:116367664-116367817 Neighboring gene predicted gene, 51782 Neighboring gene RIKEN cDNA 4933412E12 gene Neighboring gene STARR-positive B cell enhancer ABC_E10645 Neighboring gene RIKEN cDNA D630029K05 gene Neighboring gene predicted gene, 40768

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A new strategy of gene trapping in ES cells using 3'RACE. Yoshida M, et al. Transgenic Res, 1995 Jul. PMID 7655516
  2. Identification of 14-3-3epsilon substrates from embryonic murine brain. Ballif BA, et al. J Proteome Res, 2006 Sep. PMID 16944949
  3. Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Munton RP, et al. Mol Cell Proteomics, 2007 Feb. PMID 17114649
  4. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Taniwaki T, et al. Dev Growth Differ, 2005 Apr. PMID 15840001
  5. Exchangeable gene trap using the Cre/mutated lox system. Araki K, et al. Cell Mol Biol (Noisy-le-grand), 1999 Jul. PMID 10512203

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC90794

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTPase binding ISO
Inferred from Sequence Orthology
more info
  
enables guanyl-nucleotide exchange factor activity ISO
Inferred from Sequence Orthology
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables small GTPase binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables small GTPase binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in cilium assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of filopodium assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of cilium assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to motile cilium ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to organelle ISO
Inferred from Sequence Orthology
more info
  
involved_in protein targeting to membrane ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi to plasma membrane transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in proximal dendrite ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
rab-3A-interacting protein
Names
SSX2-interacting protein
gene trap PAT 12
rab3A-interacting protein
rabin-3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003950.3 → NP_001003950.1  rab-3A-interacting protein isoform 2

    See identical proteins and their annotated locations for NP_001003950.1

    Status: VALIDATED

    Source sequence(s)
    AK045783, BC080289, BM938945, BY059863
    Consensus CDS
    CCDS24186.1
    UniProtKB/Swiss-Prot
    Q68EF0
    Related
    ENSMUSP00000020375.7, ENSMUST00000020375.7
    Conserved Domains (1) summary
    pfam08614
    Location:160 → 209
    ATG16; Autophagy protein 16 (ATG16)

  2. NM_001359645.1 → NP_001346574.1  rab-3A-interacting protein isoform 1

    Status: VALIDATED

    Source sequence(s)
    AA980340, AK045783, AK152122, BM938945, BY059863
    Consensus CDS
    CCDS88090.1
    UniProtKB/TrEMBL
    A0A1W2P7K6
    Related
    ENSMUSP00000151708.2, ENSMUST00000219109.2
    Conserved Domains (2) summary
    COG4372
    Location:104 → 240
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    pfam06428
    Location:173 → 241
    Sec2p; GDP/GTP exchange factor Sec2p

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    116741685..116786361 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513546.4 → XP_006513609.1  rab-3A-interacting protein isoform X1

    See identical proteins and their annotated locations for XP_006513609.1

    UniProtKB/TrEMBL
    A0A1W2P7K6
    Conserved Domains (2) summary
    COG4372
    Location:104 → 240
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    pfam06428
    Location:173 → 241
    Sec2p; GDP/GTP exchange factor Sec2p

  2. XM_030245041.1 → XP_030100901.1  rab-3A-interacting protein isoform X2

    UniProtKB/Swiss-Prot
    Q68EF0
    Conserved Domains (1) summary
    pfam08614
    Location:160 → 209
    ATG16; Autophagy protein 16 (ATG16)

  3. XM_006513544.2 → XP_006513607.1  rab-3A-interacting protein isoform X1

    See identical proteins and their annotated locations for XP_006513607.1

    UniProtKB/TrEMBL
    A0A1W2P7K6
    Conserved Domains (2) summary
    COG4372
    Location:104 → 240
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    pfam06428
    Location:173 → 241
    Sec2p; GDP/GTP exchange factor Sec2p

  4. XM_006513547.4 → XP_006513610.1  rab-3A-interacting protein isoform X3

    Conserved Domains (1) summary
    pfam06428
    Location:4 → 72
    Sec2p; GDP/GTP exchange factor Sec2p

  5. XM_017313908.2 → XP_017169397.1  rab-3A-interacting protein isoform X4

  6. XM_006513548.5 → XP_006513611.1  rab-3A-interacting protein isoform X4

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q68EF0.1 GenPept UniProtKB/Swiss-Prot:Q68EF0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous