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Sertad4 SERTA domain containing 4 [ Mus musculus (house mouse) ]

Gene ID: 214791, updated on 5-Mar-2024

Summary

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Official Symbol
Sertad4provided by MGI
Official Full Name
SERTA domain containing 4provided by MGI
Primary source
MGI:MGI:2443496
See related
Ensembl:ENSMUSG00000016262 AllianceGenome:MGI:2443496
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4833404A09; C130018M11Rik
Summary
Predicted to be located in nucleus. Is expressed in brain. Orthologous to human SERTAD4 (SERTA domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in limb E14.5 (RPKM 33.2), CNS E18 (RPKM 10.3) and 10 other tissues See more
Orthologs
human all
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Genomic context

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Location:
1 H6; 1 97.55 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (192526796..192538060, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (192844469..192855752, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A730013G03 gene Neighboring gene RIKEN cDNA 1700065J18 gene Neighboring gene predicted gene 15867 Neighboring gene STARR-seq mESC enhancer starr_03467 Neighboring gene STARR-seq mESC enhancer starr_03468 Neighboring gene synaptotagmin XIV Neighboring gene 40S ribosomal protein S11-like Neighboring gene predicted gene, 39746

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis. Kawaguchi A, et al. Development, 2008 Sep. PMID 18725516
  2. Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor. Pilot-Storck F, et al. Mol Cell Proteomics, 2010 Jul. PMID 20368287, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
SERTA domain-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177794.1 → NP_001171265.1  SERTA domain-containing protein 4

    See identical proteins and their annotated locations for NP_001171265.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL365326, BQ174721, BX514346
    Consensus CDS
    CCDS15630.2
    UniProtKB/Swiss-Prot
    A7DTG3, Q6PAK2
    Related
    ENSMUSP00000016406.8, ENSMUST00000016406.14
    Conserved Domains (1) summary
    pfam06031
    Location:108 → 142
    SERTA; SERTA motif

  2. NM_198247.2 → NP_937890.2  SERTA domain-containing protein 4

    See identical proteins and their annotated locations for NP_937890.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL365326, BC060251
    Consensus CDS
    CCDS15630.2
    UniProtKB/Swiss-Prot
    A7DTG3, Q6PAK2
    Related
    ENSMUSP00000116176.2, ENSMUST00000155579.8
    Conserved Domains (1) summary
    pfam06031
    Location:108 → 142
    SERTA; SERTA motif

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    192526796..192538060 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006497248.4 → XP_006497311.1  SERTA domain-containing protein 4 isoform X2

    See identical proteins and their annotated locations for XP_006497311.1

    UniProtKB/Swiss-Prot
    A7DTG3, Q6PAK2
    Conserved Domains (1) summary
    pfam06031
    Location:108 → 142
    SERTA; SERTA motif

  2. XM_017319739.3 → XP_017175228.1  SERTA domain-containing protein 4 isoform X1

    Conserved Domains (1) summary
    pfam06031
    Location:170 → 204
    SERTA; SERTA motif
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A7DTG3.1 GenPept UniProtKB/Swiss-Prot:A7DTG3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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